| Project/Area Number |
26550068
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Modeling and technologies for environmental conservation and remediation
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| Research Institution | Kyushu University |
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Principal Investigator |
Nose Takeru 九州大学, 学内共同利用施設等, 教授 (10301334)
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| Co-Investigator(Kenkyū-buntansha) |
MAEDA Iori 九州工業大学, 情報工学研究院, 准教授 (50311858)
SUYAMA Keitaro 九州大学, 基幹教育院, 助教 (60707222)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 機能性分子 / 合成ペプチド / コアセルベーション / 塩析 / ペプチド |
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| Outline of Final Research Achievements |
For development of functional materials possessing metal and radioactive pollutant binding characteristics, various kinds of elastin-derived peptides with chemical modification, amino acid substitution or dimerization were synthesized. Synthesized peptides were analyzed by temperature-dependent coacervation properties with and without a series of metal salts. These peptides were easily synthesized and were stable in seawater and freshwater. When coacervation property of peptides was examined with various kinds of metallic salts, it was observed that coacervation temperature was decreased as increasing of valence of ion. These results indicated that the elastin-derived peptides interacting with ions could be separated from solution phase at low temperature and at low peptide concentration.
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