| Project/Area Number |
26560065
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
Inui Hiroshi 大阪府立大学, 総合リハビリテーション学部, 教授 (20193568)
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| Co-Investigator(Kenkyū-buntansha) |
HARADA Naoki 大阪府立大学, 生命環境科学研究科, 講師 (00529141)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 唾液 / アンドロゲン / 性差 / テストステロン / 糖鎖 / 男性ホルモン / アンドロゲン受容体 / 唾液腺 |
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| Outline of Final Research Achievements |
In this study, we examined sex-associated differences in the expression of sex hormone receptors in the salivary glands and in the abundance of secretory salivary proteins. Androgen receptor was highly expressed in the submandibular, sublingual, and parotid glands of both male and female mice. No significant differences were observed in the relative salivary glands weights of male and female mice. We have identified sex-associated bias in secretory salivary protein types. Testosterone levels in male mice were partially responsible for the sex-associated differences in the abundance of the specific salivary proteins.
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