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Bone development and the effect of Ca2+ deficiency during the pregnancy

Research Project

Project/Area Number 26560068
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Eating habits
Research InstitutionKanto Gakuin University

Principal Investigator

MOMOSE-SATO Yoko  関東学院大学, 栄養学部, 教授 (70251501)

Co-Investigator(Renkei-kenkyūsha) SATO Katsushige  駒沢女子大学, 人間健康学部, 教授 (80291342)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords骨形成 / 発生 / 染色 / マウス胚 / 鶏胚
Outline of Final Research Achievements

We examined developmental processes of bone formation in chick and mouse embryos using a bone staining method with alizarin red S. The stage of bone formation was different between regions. In the chick embryo, the first staining of the bone was observed at E (days of incubation) 12 in the maxillary, mandibular, cranial, femoral, tibial/fibulal, metatarsal, humeral, and radial/ulnal bones. In the mouse embryo, the first staining of the bone was observed at E (days of pregnancy) 14 in the mandibular bone and clavicula. In both the chick and mouse embryos, development of the cranial bone was earlier, and that of the vertebral and digit bones was later than formation of the other regions.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (18 results)

All 2017 2016 2015

All Journal Article (6 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 6 results,  Open Access: 6 results,  Acknowledgement Compliant: 6 results) Presentation (11 results) (of which Int'l Joint Research: 9 results,  Invited: 1 results) Book (1 results)

  • [Journal Article] Functiogenesis of the embryonic central nervous system revealed by optical recording with a voltage-sensitive dye.2017

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 67 Issue: 1 Pages: 107-119

    • DOI

      10.1007/s12576-016-0482-z

    • NAID

      40021064567

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Intraoperative intrinsic optical imaging of human somatosensory cortex during neurosurgical operations.2017

    • Author(s)
      Sato, K., Nariai, T., Momose-Sato, Y. and Kamino, K.
    • Journal Title

      Neurophotonics

      Volume: 4, 031205 Issue: 3 Pages: 1-5

    • DOI

      10.1117/1.nph.4.3.031205

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Oscillations in the embryonic chick olfactory bulb: initial expression and development revealed by optical imaging with a voltage-sensitive dye.2016

    • Author(s)
      Sato, K., Hayashi, S., Inaji, M. and Momose-Sato, Y.
    • Journal Title

      European Journal of Neuroscience

      Volume: 43 Issue: 8 Pages: 1111-1121

    • DOI

      10.1111/ejn.13189

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Development of synaptic networks in the mouse vagal pathway revealed by optical mapping with a voltage-sensitive dye.2016

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Journal Title

      European Journal of Neuroscience

      Volume: 44 Issue: 2 Pages: 1906-1918

    • DOI

      10.1111/ejn.13283

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Development of spontaneous activity in the avian hindbrain.2016

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 10: Article 63 Pages: 1-5

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Voltage-sensitive dye imaging during functional development of the embryonic nervous system: a brief review with special thanks to Professor Larry Cohen.2015

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Journal Title

      Neurophotonics

      Volume: 2 Issue: 2 Pages: 0210091-5

    • DOI

      10.1117/1.nph.2.2.021009

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Optical mapping of neuronal activity in the facial motor nucleus of the embryonic rat brainstem.2017

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of in ovo blockade of the spontaneous depolarization wave on the formation of synaptic networks in the embryonic brainstem.2017

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optical imaging of widely-spreading wave activity in the embryonic chick forebrain induced by olfactory nerve stimulation.2016

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      Society for Neuroscience 46th Annual Meeting.
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Voltage-sensitive dye imaging of widely-spreading wave activity in the embryonic chick forebrain induced by olfactory nerve stimulation.2016

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      第39回日本神経科学学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Widely-spreading wave activity in the embryonic chick forebrain induced by olfactory nerve stimulation: Optical imaging with a voltage-sensitive dye.2016

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      The 93rd Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of functional synaptic networks in the mouse vagal pathway: optical mapping with a voltage-sensitive dye.2015

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Organizer
      Society for Neuroscience 45th Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2015-11-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Optical analysis of developmental changes in oscillatory activity in the embryonic chick olfactory bulb.2015

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      Society for Neuroscience 45th Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2015-11-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Developmental changes in oscillatory activity in the embryonic chick olfactory bulb: Optical imaging with a voltage-sensitive dye.2015

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      The 38th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of functional synaptic networks in the mouse vagal pathway: Optical mapping with a voltage-sensitive dye.2015

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Organizer
      The 38th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Optical mapping of vagus nerve-related brainstem nuclei in the mouse embryo.2015

    • Author(s)
      Momose-Sato, Y. and Sato, K.
    • Organizer
      The 92nd Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21 – 2015-03-23
    • Related Report
      2014 Research-status Report
  • [Presentation] Functiogenesis of the embryonic CNS revealed by multiple-site optical recording with a voltage-sensitive dye.2015

    • Author(s)
      Sato, K. and Momose-Sato, Y.
    • Organizer
      The 92nd Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-03-21 – 2015-03-23
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] Membrane Potential Imaging in the Nervous System and in the Heart2015

    • Author(s)
      Momose-Sato, Y., Sato, K. and Kamino, K.
    • Total Pages
      509
    • Publisher
      Springer
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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