| Project/Area Number |
26560199
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biomedical engineering/Biomaterial science and engineering
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MIURA HIDEKAZU 東北大学, 加齢医学研究所, 助教 (50451894)
YAMBE TOMOYUKI 東北大学, 加齢医学研究所, 教授 (70241578)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
SASAKI KAZUMASU 東北大学, 加齢医学研究所, 助教 (80738948)
AKIYAMA MASATOSHI 東北大学, 心臓血管外科, 講師 (80526450)
SAIKI YOSHIKATSU 東北大学, 心臓血管外科, 教授 (50372298)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 人工臓器学 / 末梢循環 / モデリング / 循環シミュレータ |
|---|
| Outline of Final Research Achievements |
There is an increasing number of domiciliary treatment cases of patients with severe heart failure. However, it is anticipated that the deterioration of peripheral organs might be caused by the long-term rotary blood pump support. We focused on the development of a new diagnostic method for the evaluation of peripheral perfusion using a simple non-invasive imaging. By the method designed, the colour level of intensity showed blood flow perfusion which could be validated in goats’ experiments with the laser Doppler flow velocimetry. Secondly, we examined the effect of mechanical circulatory assistance ratio on peripheral perfusion by the changes in revolution numbers during the left ventricular support using a centrifugal blood pump that was connected from the apex to the descending aorta. As a result, it was indicated the system designed in the study could be useful for the evaluation of peripheral circulatory condition during mechanical circulatory support.
|
