• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of powder drugs delivery technique using micro shock tube

Research Project

Project/Area Number 26560244
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionSaga University

Principal Investigator

Hashimoto Tokitada  佐賀大学, 工学(系)研究科(研究院), 准教授 (90392860)

Research Collaborator NOHARA Naoki  
HIEDA Kensuke  
YOKOO Yuko  
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords衝撃波管 / 粉体注射 / 薬剤輸送 / 高速気流 / 固気二相流 / 薬物輸送 / 無針注射 / 粉体 / 薬物輸送システム / 超音速噴流 / 光学可視化
Outline of Final Research Achievements

In the present study, a powders injector of 180mm in total length was designed and produced using a shock tube driven supersonic jet for the development of the injection system without the needle. According to the characteristic tests of this device, nozzle reservoir pressure by shock wave reflected at the end of the low-pressure chamber is formed, and as flow Mach number is approximately 1.75 and relatively long test time is obtained when an initial pressure ratio is 9. When the powder particles are installed in the device, speed more than approximately 350 m per second is obtained. Afterward, a penetration route to the PVA hydro gel, which is used as a simulated living body, was carried out using this device. As a result, the diamater of the penetration route is 0.66 mm in average and it is possible that the penetration depth is approximately 40 mm for the case of the stand off distance between the simulated living body surface and the nozzle exit is 2 mm.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (6 results)

All 2017 2016 2015 2014 Other

All Int'l Joint Research (1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Int'l Joint Research] Andong National University(韓国)

    • Related Report
      2016 Annual Research Report
  • [Presentation] 衝撃波管駆動粉体注射器を用いた模擬生体への貫入試験2017

    • Author(s)
      横尾侑子,吉次達哉,住隆博,橋本時忠,松尾繁,瀬戸口俊明
    • Organizer
      平成28年度 衝撃波シンポジウム
    • Place of Presentation
      横須賀
    • Year and Date
      2017-03-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] 衝撃波管駆動無針注射器を使用した模擬皮膚貫入試験2016

    • Author(s)
      横尾侑子,濱田恭弘,檜枝健介,住隆博,橋本時忠,松尾繁,瀬戸口俊明
    • Organizer
      日本機械学会 九州支部第69期総会・講演会
    • Place of Presentation
      熊本,日本
    • Year and Date
      2016-03-15
    • Related Report
      2015 Research-status Report
  • [Presentation] Experimental Study on High-Speed Particle Induced by a Micro Shock Tube2015

    • Author(s)
      Tokitada Hashimoto, Kensuke Hieda, Yuko Yokoo, Shigeru Matsuo and Toshiaki Setoguchi
    • Organizer
      12th International Symposium on Experimental and Computational Aerothermodynamics of Internal Flows
    • Place of Presentation
      Lerici, Italy
    • Year and Date
      2015-07-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 衝撃波管駆動の粉体注射器の特性2015

    • Author(s)
      野原直樹,檜枝健介,横尾侑子,橋本時忠,松尾繁,瀬戸口俊明
    • Organizer
      平成 26 年度衝撃波シンポジウム
    • Place of Presentation
      群馬
    • Year and Date
      2015-03-09 – 2015-03-11
    • Related Report
      2014 Research-status Report
  • [Presentation] Fundamental study on the powder injection using a micro shock tube2014

    • Author(s)
      Naoki Nohara, Kensuke Hieda, Tokitada Hashimoto, Shigeru Matsuo, Toshiaki Setoguchi
    • Organizer
      5th Asian Joint Workshop on Thermophysics and Fluid Science
    • Place of Presentation
      Nagasaki
    • Year and Date
      2014-09-23 – 2014-09-26
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2022-02-16  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi