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To provide a renal rehabilitation program having an excellent treating or preventing effect on the physical function.

Research Project

Project/Area Number 26560271
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTohoku University

Principal Investigator

Kohzuki Masahiro  東北大学, 医学(系)研究科(研究院), 教授 (70234698)

Co-Investigator(Kenkyū-buntansha) Ito Osamu  東北大学, 医学系研究科, 准教授 (00361072)
Miura Misa  筑波技術大学, 保健科学部, 准教授 (30612014)
Mori Nobuyoshi  東北大学, 医学系研究科, 助教 (50463790)
Nagasaka Makoto  東北大学, 医学系研究科, 非常勤講師 (70375062)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords腎臓リハビリテーション / 慢性腎不全 / 糖尿病 / 慢性糸球体腎炎 / 物理療法 / 運動療法 / 進行防止 / 有酸素運動 / 慢性心不全 / 房室ブロック / ペースメーカー / 血液透析 / 電気刺激 / 腎臓機能障害 / 進行予防 / 透析導入効果 / 微弱電気刺激 / CKD患者
Outline of Final Research Achievements

Chronic kidney disease (CKD) is one of the top 10 causes of death and patients show reduced physical function and greater risk of arteriosclerosis because of hypertension, metabolic disturbances, and vascular calcification. CKD is often caused by diabetes mellitus (DM) and hypertension (HTN). Both DM and HTN are treatable and preventable and, yet, the population of individuals diagnosed with these two diseases is increasing. Millions of dollars are spent every year providing dialysis treatments for patients with CKD. This money only accounts for dialysis and does not include the millions spent on complications such as infections, medications, tests and procedures. Health promotion and early detection is a key factor in reducing the risk for and incidence of DM and HTN, thus reducing the incidence of CKD. In this study, the safety and efficacy of training and electrical stimulation during hemodialysis were confirmed without sudden drop of blood pressure or any other side effects.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (25 results)

All 2015 2014

All Journal Article (13 results) (of which Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 4 results) Book (2 results)

  • [Journal Article] Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats2015

    • Author(s)
      Ito D, Cao P, Kakihana T, Sato E, Suda C, Muroya Y, Ogawa Y, Hu G, Ishii T, Ito O, Kohzuki M, Kiyomoto H
    • Journal Title

      PLoS One

      Volume: 10 Issue: 9 Pages: 0138037-0138037

    • DOI

      10.1371/journal.pone.0138037

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 男性高血圧患者における脈波伝播速度とサルコペ ニア予備群との密接な関係.2015

    • Author(s)
      佐藤友則, 上月正博, 宗像正徳.
    • Journal Title

      日本臨床生理学会雑誌

      Volume: 45 Pages: 133-140

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dahl 食塩 感受性ラットの腎における長期的運動によるレニンーアンジオテンシン系への影響.2015

    • Author(s)
      作山晃裕, 伊藤 修, 坂田佳子, 伊藤大亮, 須田千尋, 上月正博.
    • Journal Title

      運動器リハビリテーション

      Volume: 26 Pages: 1-8

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito 0, Kohzuki M.
    • Journal Title

      F1000 Reserch

      Volume: 1 Pages: 41-41

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Classification of the physical disabilities and actual conditions of visceral impairment in Japan.2014

    • Author(s)
      Kohzuki M
    • Journal Title

      Asian Journal of Human Services

      Volume: 6 Pages: 125-137

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of electrical stimulation of the abdomen in inactive elderly patients with chronic indwelling urinary catheters.2014

    • Author(s)
      Miura M, Tanaka N, Nagasaka M, Iguchi M, Ito O, Kohzuki M.
    • Journal Title

      NTUT Education of Disabilities

      Volume: 12 Pages: 11-13

    • NAID

      120005397327

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 腎臓機能障碍者のリハビリテーション2014

    • Author(s)
      上月正博
    • Journal Title

      理学療法ジャーナル

      Volume: 48 Pages: 691-698

    • Related Report
      2014 Research-status Report
  • [Journal Article] 腎臓リハビリテーション2014

    • Author(s)
      上月正博
    • Journal Title

      The Japanease Journal of Rehabilitation Medicine

      Volume: 51 Pages: 28-32

    • Related Report
      2014 Research-status Report
  • [Journal Article] 腎臓リハビリテーションの効果と実際2014

    • Author(s)
      上月正博
    • Journal Title

      日本透析医会雑誌

      Volume: 29 Pages: 284-285

    • Related Report
      2014 Research-status Report
  • [Journal Article] 高齢腎不全患者のリハビリテーション-腎臓リハビリテーションの現状などについて-2014

    • Author(s)
      上月正博
    • Journal Title

      Mebio

      Volume: 31 Pages: 63-69

    • Related Report
      2014 Research-status Report
  • [Journal Article] 腎臓疾患のリハビリテーション2014

    • Author(s)
      上月正博
    • Journal Title

      診断と治療

      Volume: 102 Pages: 391-394

    • Related Report
      2014 Research-status Report
  • [Journal Article] 透析患者の運動療法・リハビリテーション2014

    • Author(s)
      伊藤 修
    • Journal Title

      腎と透析

      Volume: 76 Pages: 448-450

    • Related Report
      2014 Research-status Report
  • [Journal Article] 透析患者における転倒対策2014

    • Author(s)
      三浦美佐, 伊藤 修
    • Journal Title

      臨床透析

      Volume: 30 Pages: 1259-1266

    • Related Report
      2014 Research-status Report
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients: Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Hirayama Y, Ito O, Kohzuki M.
    • Organizer
      2015 American Societ of Nephrology
    • Place of Presentation
      San Diego, America
    • Year and Date
      2015-11-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Pitavastatin prevents development of hypertension with upregulation of nitric oxide synthases in the kidney of spontaneously hypertensive rats.2015

    • Author(s)
      Hu G, Ito O, Rong R, Xu B, Sakuyama A, Sakata Y, Ito D, Kohzuki M.
    • Organizer
      American Heart Association High Blood Pressure Research 2015 Scientific Sessions
    • Place of Presentation
      Washington DC, America
    • Year and Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chronic kidney disease -a new target of cardiac rehabilitation.2015

    • Author(s)
      Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of Aerobic Training and Electrical Stimulation to Skeletal Muscles during Hemodialysis for Patients with End-Stage Renal Disease.2015

    • Author(s)
      Miura M, Kohzuki M, Oowada S, Hirayama S, Ito O.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      52th ERA-EDTA
    • Place of Presentation
      London, England
    • Year and Date
      2015-05-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] らくらく運動・ながら運動の時代:負荷量可変式エルゴメータの将来性2015

    • Author(s)
      上月正博.
    • Organizer
      日本医工学治療学会第31回学術大会
    • Place of Presentation
      広島、広島国際会議場
    • Year and Date
      2015-03-27 – 2015-03-29
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 血液透析中の運動療法と下肢電気刺激が身体に与える影響2015

    • Author(s)
      三浦美佐
    • Organizer
      第5回日本腎臓リハビリテーション学会
    • Place of Presentation
      東京、都市センターホテル
    • Year and Date
      2015-03-21 – 2015-03-22
    • Related Report
      2014 Research-status Report
  • [Presentation] Effects of aerobic training on exercise tolerance and the autonomic nervous activity in patients with chronic kidney disease.2014

    • Author(s)
      Miura M
    • Organizer
      Asian Preventive Cardiology & Cardiac Rehabilitation Conference
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2014-11-06 – 2014-11-09
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 慢性腎臓病の心臓リハビリテーションのエビデンス.2014

    • Author(s)
      上月正博.
    • Organizer
      第20回日本心臓 リハビリテーション学会
    • Place of Presentation
      京都、みやこめっせ
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 運動療法・リハビリテーションを考える.2014

    • Author(s)
      上月正博.
    • Organizer
      第59回日本透析医学会
    • Place of Presentation
      神戸、神戸国際会議場
    • Year and Date
      2014-06-12 – 2014-06-15
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] 重複障害のリハビリテーション2015

    • Author(s)
      上月正博.
    • Total Pages
      581
    • Publisher
      三輪書店
    • Related Report
      2015 Annual Research Report
  • [Book] イラストでわかる 患 者さんのための心臓リハビリ入門 第3版2015

    • Author(s)
      伊藤 修, 上月正博, 小川佳子, 鈴木文歌, 吉田俊子.
    • Total Pages
      122
    • Publisher
      中外医学社
    • Related Report
      2015 Annual Research Report

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Published: 2014-04-04   Modified: 2017-05-10  

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