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Motor imagery with muscle afferent stimulation elicits the voluntary-like reflex movement after its training.

Research Project

Project/Area Number 26560282
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKyorin University

Principal Investigator

Nakajima Tsuyoshi  杏林大学, 医学部, 助教 (60435691)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords神経システム再構築 / ニューロリハビリテーション / 脊髄 / 脊髄障害 / 運動イメージ / 神経リハビリテーション / 脊髄反射回路 / 脊髄可塑性 / 脊髄神経機構 / 随意運動回復 / 反射回路 / 神経リハビリテーション法 / 痙縮制御
Outline of Final Research Achievements

The purpose of the present study was to examine whether the voluntary movement-like reflex force could be produced by the motor imagery under the weak high frequency stimulation of muscle afferents. While the stimulation were applied to tibial nerve (3 Hz), small repetitive twitch forces of plantar flexion (PF) arising from monosynaptic reflex were elicited from triceps surae. Under this situation, the subjects were asked to imagine motor execution of PF. As a result of physiological and kinematical analyses, this new stimulation technique with imagery of motor execution occurred smooth ramp increment movement (gradual enhancement of repetitive reflex twitches) after ~100 times of training. Furthermore, actual “voluntary movement” could be improved (i.e. reduction of movement discontinuity). These results suggested that motor imagery with high frequency stimulation can induce voluntary-like reflex movement after this training, and modulate actual motor performance itself.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (11 results)

All 2017 2016 2015

All Journal Article (4 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Acknowledgement Compliant: 4 results,  Open Access: 3 results) Presentation (7 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results)

  • [Journal Article] Reassessment of non-monosynaptic excitation from the motor cortex to motoneurons in single motor units of the human biceps brachii2017

    • Author(s)
      T. Nakajima, T. Tazoe, M. Sakamoto, T. Endoh, S. Shibuya, L.A. Elias, R.A. Mezzarane, T. Komiyama and Y. Ohki
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 11 Pages: 19-19

    • DOI

      10.3389/fnhum.2017.00019

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Vestibular stimulation-induced facilitation of cervical premotoneuronal systems in humans.2017

    • Author(s)
      S. Suzuki, T. Nakajima, S. Irie, R. Ariyasu, T. Komiyama and Y. Ohki.
    • Journal Title

      PlosOne

      Volume: 12(4) Issue: 4 Pages: e0175131-e0175131

    • DOI

      10.1371/journal.pone.0175131

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Neural mechanisms underlying reversal of cutaneous reflexes during human bipedal walking2016

    • Author(s)
      Tsuyoshi Nakajima, Shinya Suzuki, Genki Futatsubashi, Hiroyuki Ohtsuska2,4, Rinaldo A. Mezzarane, Trevor S. Barss, Taryn Klarner, E. Paul Zehr and Tomoyoshi Komiyama
    • Journal Title

      Journal of Neurophysiology

      Volume: In press Issue: 1 Pages: 1-25

    • DOI

      10.1152/jn.01011.2015

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Short-term plasticity in a monosynaptic reflex pathway to forearm muscles after continuous robot-assisted passive stepping.2016

    • Author(s)
      Nakajima T, Kamibayashi K, Kitamura T, Komiyama T, Zehr EP, Nakazawa K.
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 10 Pages: 368-368

    • DOI

      10.3389/fnhum.2016.00368

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Motor imagery of cuscle contraction is available to induce long-lasting potentiation in indirect cortico-motoneuronal excitation in a relaxed muscle.2016

    • Author(s)
      Irie S, Nakajima T, Suzuki S, Ariyasu R, Komiyama T, Ohki Y
    • Organizer
      Neuroscience 2016
    • Place of Presentation
      アメリカ サンディエゴ
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒト脊髄内の代替神経機構を強化する運動機能の回復戦略2016

    • Author(s)
      中島 剛, 小宮山伴与志, 大木 紫
    • Organizer
      早稲田スポーツサイエンス研究会
    • Place of Presentation
      所沢
    • Year and Date
      2016-10-13
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] ヒト脊髄内の代替神経機構を強化する運動機能の回復戦略、 シンポジウム5 「運動生理学における神経系研究の最新トピック~ヒトの巧みな動作を支える神経適応能」2016

    • Author(s)
      中島 剛, 小宮山伴与志, 大木 紫
    • Organizer
      第24回日本運動生理学会大会
    • Place of Presentation
      熊本
    • Year and Date
      2016-07-23
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Vestibular stimulation facilitates cervical interneuronal systems mediating corticospinal excitation to arm motoneurons in humans2016

    • Author(s)
      Suzuki S, Nakajima T, Irie S, Ariyasu R, Komiyama T, Ohki Y
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Long-lasting potentiation on indirect cortico-motoneuronal excitation in a relaxed muscle could be induced by use of motor imagery.2016

    • Author(s)
      Irie S, Nakajima T. Suzuki S., Ariyasu R., Komiyama T, Ohki Y
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒト前庭刺激を利用した安静筋における間接的皮質脊髄路の長期増強.2015

    • Author(s)
      鈴木伸弥, 中島剛, 入江駿, 一寸木洋平, 小宮山伴与志, 大木紫.
    • Organizer
      第38回日本神経科学学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report
  • [Presentation] ヒトの間接的皮質-脊髄路への抑制性システムの可塑的変化.2015

    • Author(s)
      中島剛, 鈴木伸弥, 二橋元紀, 入江駿, 小宮山伴与志, 大木紫.
    • Organizer
      第38回日本神経科学学会,
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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