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Development of a screening test to predict acute mountain sickness

Research Project

Project/Area Number 26560349
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionNagoya University

Principal Investigator

Ishida Koji  名古屋大学, 総合保健体育科学センター, 教授 (50193321)

Co-Investigator(Kenkyū-buntansha) 片山 敬章  名古屋大学, 総合保健体育科学センター, 准教授 (40343214)
佐藤 耕平  日本女子体育大学, 体育学部, 准教授 (00409278)
Co-Investigator(Renkei-kenkyūsha) SHIMAOKA Kiyoshi  東海学園大学, スポーツ健康科学部, 教授 (60109361)
OKAZAKI Kazunobu  大阪市立大学, 都市健康・スポーツ研究センター, 准教授 (70447754)
Research Collaborator YAMAUCHI Koun  名古屋大学, 医学系研究科, 大学院生
ITO Yuka  名古屋大学, 医学系研究科, 大学院生
GOTO Kanako  名古屋大学, 医学系研究科, 大学院生
ITO Hatsue  名古屋大学, 医学系研究科, 大学院生
SHIMIZU Kaori  名古屋大学, 教育発達科学研究科, 大学院生
CHO Rogyoku  名古屋大学, 総合保健体育科学センター, 研究生
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords急性高山病 / スクリーニングテスト / 低酸素運動 / 動脈血酸素飽和度 / 呼吸循環応答 / 高所登山 / 中高年登山家 / 換気応答 / 低酸素 / 酸素漸減 / 酸素急減 / AMSスコア / 低酸素環境 / 循環応答 / 脳血流
Outline of Final Research Achievements

In order to develop a screening test to predict who is more likely to suffer from acute mountain sickness (AMS), we examined the cardio-respiratory responses to acute and gradual (1%/min) decrease in inspired oxygen content (12-13%) during middle intensity (35-40%max) exercise at sea level and compared these between the subjects who had suffered and not suffered from AMS at high altitude. We recruited two subjects’ group, one was the university students who had climbed the same high mountain (3000m) and the other was the middle-aged and elderly who have well experienced in high mountains above 2500m. The results suggested that we had better adopt the gradual hypoxic protocol based on subjects’ comfort and safety, and that people whose arterial oxygen saturation falls rapidly and below 75% during hypoxic exercise, or whose minute ventilation and end-tidal CO2 partial pressure at each stage show lower and higher value respectively should be susceptible to AMS at high altitude.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (7 results)

All 2016 2015 2014 Other

All Presentation (5 results) (of which Int'l Joint Research: 1 results) Remarks (2 results)

  • [Presentation] 急性高山病 (AMS)に対するスクリーニングテストの開発2016

    • Author(s)
      山内高雲, 片山敬章, 原 明, 松岡敏男, 石田浩司
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県盛岡市
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] Cardiorespiratory responses to gradual and acute hypoxia during constant load exercise.2016

    • Author(s)
      Ishida K., Yamauchi K., Sato K., and Katayama K.
    • Organizer
      21st Annual Meeting of the European College of Sports Science
    • Place of Presentation
      VIenna, Austria
    • Year and Date
      2016-07-06
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 運動中の酸素濃度急減および漸減に対する呼吸循環応答の比較2015

    • Author(s)
      石田浩司,山内高雲,伊藤佑華,片山敬章,佐藤耕平
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 運動中の急性低酸素暴露に対する脳血流量の経時的変化2015

    • Author(s)
      山内高雲,佐藤耕平,片山敬章,伊藤佑華,石田浩司
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 短期間の低酸素トレーニングによる運動時換気亢進の学習効果2014

    • Author(s)
      石田浩司,片山敬章,小池晃彦,山内高雲,伊藤佑華,堀田典生,岩本えりか
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
  • [Remarks] 急性高山病とは

    • URL

      http://www.htc.nagoya-u.ac.jp/~ishida/Personal/Investigation/AMS.html

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Remarks] 低酸素に対する生体の応答と急性高山病について

    • URL

      http://www.htc.nagoya-u.ac.jp/~ishida/Personal/Investigation/hypoxia

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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