| Project/Area Number |
26560353
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | National Institute of Fitness and Sports in Kanoya |
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Principal Investigator |
MIYAMOTO NAOKAZU 鹿屋体育大学, スポーツ生命科学系, 准教授 (20420408)
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| Co-Investigator(Kenkyū-buntansha) |
橋本 健志 立命館大学, スポーツ健康科学部, 教授 (70511608)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 低酸素 / 筋肥大 / 骨格筋 / 骨格筋細胞 / 分化 / 筋酸素飽和度 / 筋疲労 |
|---|
| Outline of Final Research Achievements |
We first examined how exposure of skeletal muscle cells to hypoxic environment affects muscle differentiation (Study 1). In Study 2, based on the results of Study 1, we examined the usefulness of resistance training under hypoxic environment to muscle hypertrophy in human in vivo. In Study 1, muscle differentiation was delayed or inhibited under a severe hypoxic condition, whereas hypertrophy of skeletal muscle fibers was observed under a mild hypoxic condition. In Study 2, resistance training load (load and repetition) was not changed in an appropriate hypoxic condition.
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