development of in vivo imaging system for skeletal muscle biology
Project/Area Number |
26560394
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Applied health science
|
Research Institution | The University of Tokyo |
Principal Investigator |
AKIMOTO Takayuki 東京大学, 医学(系)研究科(研究院), 講師 (00323460)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | in vivoイメージング / 筋 / シグナル伝達 / 動的環境 / メカニカルストレス / 動的状態 |
Outline of Final Research Achievements |
We developed an in vivo imaging system to combine spining-disc conforcal system with sensitive CCD camera. As a result of this project, we observed that the Nuclear factor of activated T-cells(NFAT)were translocated into nucleus in response to muscle contraction in adult skeletal muscle. We will apply this technique to see various phenomena in skeletal muscle in near the future
|
Report
(3 results)
Research Products
(1 results)