Exosome-mediated intercellular chemical signals

Research Project

Project/Area Number	26560427
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Multi-year Fund
Research Field	Biomolecular chemistry
Research Institution	Tohoku University
Principal Investigator	Ueda Minoru 東北大学, 理学(系)研究科(研究院), 教授 (60265931)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000) Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	エクソソーム / 天然物 / 生理活性物質 / 低分子 / 分泌 / 輸送 / エキソソーム / 細胞間コミュニケーション / メタボローム
Outline of Final Research Achievements	The search for novel bioactive substance becomes more difficult. We focused on an exosome which is known as a liposomal transport system between cells like a "message in a bottle" between cell. We purified mammalian liposome and tried to analyze the involved secondary metabolites. However, the huge amount of biomolecules, such as RNAs, make the MS-analysis difficult.

Report

(3 results)