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Mapping human brain connectivity by analyzing spontaneous and stimulation-induced neural oscillations

Research Project

Project/Area Number 26560465
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Brain biometrics
Research InstitutionKyoto University

Principal Investigator

Matsumoto Riki  京都大学, 医学(系)研究科(研究院), 准教授 (00378754)

Co-Investigator(Kenkyū-buntansha) KUNIEDA Takeharu  京都大学, 大学院医学研究科, 講師 (60609931)
SHIMOTAKE Akihiro  京都大学, 大学院医学研究科, 助教 (80726000)
INOUCHI Morito  京都大学, 大学院医学研究科, 助教 (30532600)
KOBAYASHI Katsuya  京都大学, 大学院医学研究科, 助教 (70737121)
Co-Investigator(Renkei-kenkyūsha) IKEDA Akio  京都大学, 大学院医学研究科, 教授 (90212761)
OKADA Tomohisa  京都大学, 大学院医学研究科, 准教授 (30321607)
MATSUHASHI Masao  京都大学, 大学院医学研究科, 准教授 (40456885)
Research Collaborator USAMI Kiyohide  Johns Hopkins University, Department of Neurology, Visiting scientist
YAMAO Yukihiro  前King's College London, Visiting Researcher
NAKAE Takuro  京都大学, 大学院医学研究科, 大学院生
TOGO Masaya  京都大学, 大学院医学研究科, 大学院生
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords機能的結合 / 脳機能計測 / 皮質皮質間誘発電位 / 安静時機能MRI / 高周波律動 / てんかん / 睡眠 / 皮質間ネットワーク / 皮質間結合 / 皮質電気刺激
Outline of Final Research Achievements

Recent development in biological signal analysis has enabled us to explore much wider range of neural oscillation in living human brains, ranging from very low frequency oscillation (<0.1 Hz) of BOLD signal to high frequency activities (>100 Hz) recorded in electrocorticogram. In this study, we recruited patients with epilepsy and tumor who underwent invasive presurgical evaluation with intracranial electrodes. We first non-invasively obtained resting state fMRI data before surgery. We then, during electrode implantation, applied single-pulse electrical stimulation to a part of the cortices to record cortico-cortical evoked potentials or induced neural oscillations through cortico-cortical connections. We focused on the physiological (sleep) and pathologic (epilepsy) states and revealed their network dynamics. We also launched comprehensive investigation to establish the human brain connectivity map, focusing on the higher brain functions relevant to clinical system neuroscience.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (102 results)

All 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (33 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 23 results,  Open Access: 22 results,  Acknowledgement Compliant: 6 results) Presentation (45 results) (of which Int'l Joint Research: 6 results,  Invited: 18 results) Book (20 results) Remarks (3 results)

  • [Int'l Joint Research] マンチェスター大学(University of Manchester)(英国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Network specific change in white matter integrity in mesial temporal lobe epilepsy.2016

    • Author(s)
      Imamura, H., R. Matsumoto, S. Takaya, T. Nakagawa, A. Shimotake, T. Kikuchi, N. Sawamoto, T. Kunieda, N. Mikuni, S. Miyamoto, H. Fukuyama, R. Takahashi and A. Ikeda
    • Journal Title

      Epilepsy Research

      Volume: 120 Pages: 65-72

    • DOI

      10.1016/j.eplepsyres.2015.12.003

    • NAID

      120005749848

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The ‘when’and ‘where’of semantic coding in the anterior temporal lobe: temporal representational similarity analysis of electrocorticogram data2016

    • Author(s)
      Chen Y, Shimotake A, Matsumoto R, Kunieda T, Kikuchi T, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A, Lambon-Ralph MA
    • Journal Title

      Cortex

      Volume: 印刷中 Pages: 1-13

    • DOI

      10.1016/j.cortex.2016.02.015

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Benign adult familial myoclonus epilepsy is a progressive disorder: no longer idiopathic generalized epilepsy.2016

    • Author(s)
      Hitomi T, Kobayashi K, Sakurai T, Ueda S, Jingami N, Kanazawa K, Matsumoto R, Takahashi R, Ikeda A.
    • Journal Title

      Epileptic Disord

      Volume: 18(1) Issue: 1 Pages: 67-72

    • DOI

      10.1684/epd.2016.0807

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] てんかん外科における術前皮質・白質機能マッピング(特集:神経生理最前線)2016

    • Author(s)
      松本理器、下竹昭寛、山尾幸広、國枝武治
    • Journal Title

      最新精神医学

      Volume: 21 Pages: 101-109

    • Related Report
      2015 Annual Research Report
  • [Journal Article] てんかん病態下の脳内ネットワーク2016

    • Author(s)
      十川純平、松本理器、池田昭夫
    • Journal Title

      Clinical Neuroscience

      Volume: 34

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 皮質電気刺激によるヒト脳機能ネットワークの探索2016

    • Author(s)
      山尾幸広、國枝武治、松本理器
    • Journal Title

      脳神経外科速報

      Volume: 25 Pages: 411-420

    • NAID

      130005153208

    • Related Report
      2015 Annual Research Report
  • [Journal Article] くすぶり型辺縁系脳炎と自律神経2016

    • Author(s)
      武山博文、松本理器、池田昭夫
    • Journal Title

      神経内科

      Volume: 84 Pages: 58-61

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Different Mode of Afferents Determines the Frequency Range of High Frequency Activities in the Human Brain: Direct Electrocorticographic Comparison between Peripheral Nerve and Direct Cortical Stimulation2015

    • Author(s)
      Kobayashi K, Matsumoto R, Matsuhashi M, Usami K, Shimotake A, Kunieda T, Kikuchi T, Mikuni N, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A
    • Journal Title

      PLoS One

      Volume: 10 (6) Issue: 6 Pages: e0130461-e0130461

    • DOI

      10.1371/journal.pone.0130461

    • NAID

      120005674657

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sleep modulates cortical connectivity and excitability in humans: Direct evidence from neural activity induced by single-pulse electrical stimulation.2015

    • Author(s)
      Usami K, Matsumoto R, Kobayashi K, Hitomi T, Shimotake A, Kikuchi T, Matsuhashi M, Kunieda T, Mikuni N, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A.
    • Journal Title

      Hum Brain Mapp

      Volume: 36(11) Issue: 11 Pages: 4714-4729

    • DOI

      10.1002/hbm.22948

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Direct Exploration of the Role of the Ventral Anterior Temporal Lobe in Semantic Memory: Cortical Stimulation and Local Field Potential Evidence From Subdural Grid Electrodes2015

    • Author(s)
      Shimotake A, Matsumoto R, Ueno T, Kunieda T, Saito S, Hoffman P, Kikuchi T, Fukuyama H, Miyamoto S, Takahashi R, Ikeda A, Lambon Ralph MA
    • Journal Title

      Cerebral Cortex

      Volume: 印刷中 Issue: 10 Pages: 3802-3817

    • DOI

      10.1093/cercor/bhu262

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Proceedings of the Seventh International Workshop on Advances in Electrocorticography.2015

    • Author(s)
      Ritaccio A, Matsumoto R, Morrell M, Kamada K, Koubeissi M, Poeppel D, Lachaux JP, Yanagisawa Y, Hirata M, Guger C, Schalk G
    • Journal Title

      Epilepsy Behav

      Volume: 51 Pages: 312-320

    • DOI

      10.1016/j.yebeh.2015.08.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] New Approach for Exploring Cerebral Functional Connectivity: Review of Cortico-cortical Evoked Potential2015

    • Author(s)
      Kunieda T, Yamao Y, Kikuchi T, Matsumoto R
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 55 Issue: 5 Pages: 374-382

    • DOI

      10.2176/nmc.ra.2014-0388

    • NAID

      130005069876

    • ISSN
      0470-8105, 1349-8029
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reply to Commentary on "Neural correlates of mirth and laughter: a direct electrical cortical stimulation study"2015

    • Author(s)
      Yamao Y, Kunieda T, Matsumoto R
    • Journal Title

      Cortex

      Volume: 印刷中 Pages: 244-246

    • DOI

      10.1016/j.cortex.2015.03.019

    • NAID

      120005749925

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Network hyperexcitability in a patient with partial reading epilepsy: Converging evidence from magnetoencephalography, diffusion tractography, and functional magnetic resonance imaging2015

    • Author(s)
      Fumuro T, Matsumoto R, Shimotake A, Matsuhashi M, Inouchi M, Urayama S, Sawamoto N, Fukuyama H, Takahashi R, Ikeda A
    • Journal Title

      Clinical Neurophysiology

      Volume: 126 (4) Issue: 4 Pages: 675-681

    • DOI

      10.1016/j.clinph.2014.07.033

    • NAID

      120005625620

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A possible variant of negative motor seizure arising from the supplementary negative motor area.2015

    • Author(s)
      Yamao Y, Matsumoto R, Kunieda K, Arakawa Y, Kikuchi T, Shibata S, Ikeda A, Fukuyama H, Miyamoto S
    • Journal Title

      Clin Neurol Neurosurg

      Volume: 134 Pages: 126-129

    • DOI

      10.1016/j.clineuro.2015.04.024

    • NAID

      120005749924

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Possible induction of multiple seizure foci due to parietal tumour and anti-NMDAR antibody2015

    • Author(s)
      Matsumoto R, Mikuni N, Tanaka K, Usami K, Fukao K, Kunieda T, Takahashi Y, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A
    • Journal Title

      Epileptic Disorders

      Volume: 17 (1) Issue: 1 Pages: 89-94

    • DOI

      10.1684/epd.2015.0725

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Alpha-band desynchronization in human parietal area during reach planning2015

    • Author(s)
      Fumuro T, Matsuhashi M, Miyazaki T, Inouchi M, Hitomi T, Matsumoto R, Takahashi R, Fukuyama H, Ikeda A
    • Journal Title

      Clinical Neurophysiology

      Volume: 126(4) Issue: 4 Pages: 756-762

    • DOI

      10.1016/j.clinph.2014.07.026

    • NAID

      120005661555

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] システム神経科学とてんかんの接点2015

    • Author(s)
      松本理器、國枝武治、池田昭夫
    • Journal Title

      最新医学

      Volume: 70 Pages: 1051-1060

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
  • [Journal Article] EMUの整備と課題2015

    • Author(s)
      池田昭夫、松本理器、國枝武治
    • Journal Title

      Epilepsy

      Volume: 9 Pages: 23-28

    • NAID

      40020489939

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 思春期・成人発症てんかんの治療 (特集 てんかん : 基礎・臨床研究の最新知見)2015

    • Author(s)
      井上岳司、松本理器、池田昭夫
    • Journal Title

      日本臨床

      Volume: 72 Pages: 853-858

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
  • [Journal Article] Risk factors for infective complications with long term subdural electrode implantation in patients with medically intractable partial epilepsy.2015

    • Author(s)
      Shibata, S., T. Kunieda, R. Inano, M. Sawada, Y. Yamao, T. Kikuchi, R. Matsumoto, A. Ikeda, R. Takahashi, N. Mikuni, J. Takahashi and S. Miyamoto
    • Journal Title

      World Neurosurg

      Volume: - Issue: 2 Pages: 320-326

    • DOI

      10.1016/j.wneu.2015.03.048

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] New Approach for Exploring Cerebral Functional Connectivity: Review of CCEP (Cortico-cortical evoked potential)2015

    • Author(s)
      Kunieda T, Yamao Y, Kikuchi T, Matsumoto R
    • Journal Title

      Neurol Med Chir (Tokyo)

      Volume: 印刷中

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intracranially recorded ictal direct current shifts may precede high frequency oscillations in human epilepsy.2015

    • Author(s)
      Kanazawa K, Matsumoto R, Imamura H, Matsuhashi M, Kikuchi T, Kunieda T, Mikuni N, Miyamoto S, Takahashi R, Ikeda A.
    • Journal Title

      Clin Neurophysiol.

      Volume: 126 Issue: 1 Pages: 47-59

    • DOI

      10.1016/j.clinph.2014.05.028

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neural correlates of mirth and laughter: A direct electrical cortical stimulation study.2014

    • Author(s)
      Yamao, Y., R. Matsumoto, T. Kunieda, S. Shibata, A. Shimotake, T. Kikuchi, T. Satow, N. Mikuni, H. Fukuyama, A. Ikeda and S. Miyamoto
    • Journal Title

      Cortex

      Volume: - Pages: 134-40

    • DOI

      10.1016/j.cortex.2014.11.008

    • NAID

      120005749923

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effect of CYP2C19 polymorphisms on the clinical outcome of low-dose clobazam therapy in Japanese patients with epilepsy2014

    • Author(s)
      Hashi S, Yano I, Shibata M, Masuda S, Kinoshita M, Matsumoto R, Ikeda A, Takahashi R, Matsubara K.
    • Journal Title

      Eur J Clin Pharmacol

      Volume: 37 Issue: 1 Pages: 51-58

    • DOI

      10.1007/s00228-014-1773-z

    • NAID

      120005657893

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant2014

    • Author(s)
      Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, Asano T, Shodai A, Fujita T, Fukui S, Morino H, Nakano S, Kusaka H, Yamashita H, Ihara M, Matsumoto R, Kawamata J, Urushitani M, Kawakami H, Takahashi R.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 2 Issue: 1 Pages: 172-185

    • DOI

      10.1186/s40478-014-0172-0

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Persistent frequent subclinical seizures and memory impairment after clinical remission in smoldering limbic encephalitis2014

    • Author(s)
      Kyoko Kanazawa, Riki Matsumoto, Akihiro Shimotake, Masako Kinoshita, Akiko Otsuka, Osamu Watanabe, Keiko Tanaka, Ryosuke Takahashi, Akio Ikeda
    • Journal Title

      Epileptic Disord

      Volume: 16 Issue: 3 Pages: 312-317

    • DOI

      10.1684/epd.2014.0664

    • NAID

      120005619788

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long-term follow-up of cortical hyperexcitability in Japanese Unverricht-Lundborg disease.2014

    • Author(s)
      Kobayashi K, Hitomi T, Matsumoto R, Kondo T, Kawamata J, Matsuhashi M, Hashimoto S, Ikeda H, Koide Y, Inoue Y, Takahashi R, Ikeda A.
    • Journal Title

      Seizure

      Volume: 23 Issue: 9 Pages: 746-750

    • DOI

      10.1016/j.seizure.2014.06.002

    • NAID

      120005512264

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intraoperative dorsal language network mapping by using single-pulse electrical stimulation.2014

    • Author(s)
      Yamao Y, Matsumoto R, Kunieda T, Arakawa Y, Kobayashi K, Usami K, Shibata S, Kikuchi T, Sawamoto N, Mikuni N, Ikeda A, Fukuyama H, Miyamoto S.
    • Journal Title

      Hum Brain Mapp

      Volume: 印刷中 Issue: 9 Pages: 74-85

    • DOI

      10.1002/hbm.22479

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 急性無菌性髄膜脳炎の経過中に局所性皮質反射性ミオクローヌスを 呈し抗グルタミン酸受容体抗体が検出された 2 例2014

    • Author(s)
      戸島麻耶,人見 健文,陣上直人,谷岡洸介,山門穂高,松本理器,高橋幸利,池田昭夫,髙橋良輔
    • Journal Title

      臨床神経

      Volume: 54 Pages: 543-549

    • NAID

      130004678995

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 脳のゆらぎ・同期・オシレーション C. ヒトでの計測 6. 皮質脳波2014

    • Author(s)
      小林勝哉、松本理器
    • Journal Title

      Clinical Neuroscience

      Volume: 32 Pages: 792-796

    • Related Report
      2014 Research-status Report
  • [Journal Article] 側頭葉てんかんの認知機能と扁桃体2014

    • Author(s)
      武山博文、松本理器、三枝隆博、池田昭夫
    • Journal Title

      Clinical Neuroscience

      Volume: 32 Pages: 680-682

    • Related Report
      2014 Research-status Report
  • [Journal Article] 家族性側頭葉てんかん2014

    • Author(s)
      麓直浩、松本理器、池田昭夫
    • Journal Title

      日本臨床 神経症候群(第2版)VI

      Volume: 別冊 Pages: 413-416

    • Related Report
      2014 Research-status Report
  • [Presentation] Intracranially recorded ictal DC shifts and HFOs as surrogate markers of epileptogenicity in human focal epilepsy.2016

    • Author(s)
      Daifu M, Inouchi M, Kanazawa K, Matsuhashi M, Inoue T, Kobayashi K, Shimotake A, Hitomi T, Matsumoto R, Kunieda T, Miyamoto S, Takahashi R, Ikeda A.
    • Organizer
      2nd International workshop on High Frequency Oscillations in Epilepsy
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      2016-03-10
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The ventral language network - its function, connectivity and plasticity: insights from direct cortical stimulation and ECoG recordings.2015

    • Author(s)
      Matsumoto R.
    • Organizer
      Special Seminar at Cognitive Neurophysiology and Brain&#8211;Machine Interface Laboratory
    • Place of Presentation
      Department of Neurology, Johns Hopkins Hospital, Baltimore, USA
    • Year and Date
      2015-12-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 皮質・皮質間誘発電位(CCEP)記録・解析の実際2015

    • Author(s)
      松本理器、國枝武治、池田昭夫
    • Organizer
      第45回日本臨床神経生理学会学術大会ワークショップ4.皮質・皮質間誘発電位
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ヒト内側頭頂葉の機能的結合性:皮質―皮質間誘発電位を用いた検討2015

    • Author(s)
      十河正弥、松本理器、武山博文、小林勝哉、下竹昭寛、宇佐美清英、中江卓郎、國枝武治、宮本享、高橋良輔、池田昭夫
    • Organizer
      第45回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 慢性電極留置におけるてんかん原性評価2015

    • Author(s)
      小林勝哉、松本理器、國枝武治、池田昭夫
    • Organizer
      第45回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 術中電気的線維追跡法を用いた腹側言語経路の検討2015

    • Author(s)
      中江卓郎、松本理器、國枝武治、荒川芳輝、下竹昭寛、小林勝哉、稲野理賀、西田誠、高橋由紀、稲田拓、菊池隆幸、松橋眞生、高橋良輔、池田昭夫、宮本享
    • Organizer
      第45回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] Functional connectivity of the human entorhinal cortex: a cortico-cortical evoked potential study.2015

    • Author(s)
      Takeyama H, Matsumoto R, Kobayashi K, Usami K, Shimotake A, Kikuchi T, Kunieda T, Miyamoto S, Takahashi R, Ikeda A.
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 睡眠と前頭葉てんかん2015

    • Author(s)
      小林勝哉、松本理器、宇佐美清英、國枝武治、池田昭夫
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 側頭葉底部前方領域での意味認知機能 マッピング:事象関連電位の皮質記録の検討2015

    • Author(s)
      下竹昭寛、松本理器、太田真紀子、國枝武治、三國信啓、宮本亨、高橋良輔、池田昭夫
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高齢者のてんかん重積状態における頭部MRI拡散強調画像:臨床・脳波所見との相関2015

    • Author(s)
      吉村 元、松本 理器、上田 浩之、藤原 悟、上田 哲大、引網 亮太、村瀬 翔、石井 淳子、河野 智之、星 拓、藤堂 謙一、川本 未知、有吉 孝一、池田 昭夫、幸原 伸夫
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] VNSの効果作動機構の検討(シンポジウム4)2015

    • Author(s)
      池田昭夫、Bayasgalan Borgil, 松橋眞生、文室知之、中野直樹、飯田幸治、片桐匡弥、松本理器、國枝武治、加藤天美、髙橋良輔
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Co-occurrence of slow shifts and high frequency oscillations(HFOs) in invasively recorded, interictal state: Is it called 'Red slow'?2015

    • Author(s)
      Daifu M, Inouchi M, Inoue T, Kanazawa K, Matsuhashi M, Kobayashi K, Shimotake A, Hitomi T, Matsumoto R, Kunieda T, Miyamoto S, Takahashi R, Ikeda A.
    • Organizer
      第49回日本てんかん学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 意味認知の機能可塑性:側頭葉腫瘍切除症例における神経心理学的検討2015

    • Author(s)
      中江卓郎、國枝武治、松本理器、荒川芳輝、西田誠、稲野理賀、高橋由紀、稲田拓、下竹昭寛、菊池隆幸、吉田和道、高木康志、池田昭夫、宮本享
    • Organizer
      日本脳神経外科学会第74回学術総会
    • Place of Presentation
      札幌(さっぽろ芸術文化の館)
    • Year and Date
      2015-10-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Status epilepticus in the elderly in the super-aging society: clinical and EEG features and prognostic factors.2015

    • Author(s)
      Yoshimura H, Matsumoto R, Ishii J, Kono T, Hoshi T, Todo K, Kawamoto M, Ariyoshi K, Ikeda A, Kohara N.
    • Organizer
      31st International Epilepsy Congress
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2015-09-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Non-structural evidence of seizure focus: The role of functional imaging.2015

    • Author(s)
      Ikeda A.
    • Organizer
      31st International Epilepsy Congress
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2015-09-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Clinical implications of intraoperative CCEP monitoring in evaluating the white matter functional integrity of the dorsal language network.2015

    • Author(s)
      Matsumoto R, Yamao Y, Kunieda T, Arakawa Y, Shimotake A, Kikuchi T, Shibata S, Inano R, Sawamoto N, Ikeda A, Mikuni N, Miyamoto S.
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸(Kobe)神戸コンベンションセンター
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] Kanji word processing in the ventral anterior temporal lobe: a postoperative neuropsychological study in patients with temporal lobe epilepsy.2015

    • Author(s)
      Ota M, Matsumoto R, Shimotake A, Daifu M, Kunieda T, Miyamoto S, Takahashi R, Lambon-Ralph MA, Ikeda A.
    • Organizer
      第38回日本神経科学学会(Neuroscience 2015)
    • Place of Presentation
      神戸(Kobe)神戸コンベンションセンター
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] The when and where of semantics in the anterior temporal lobe: temporal representational similarity analysis of electrocorticogram data.2015

    • Author(s)
      Shimotake A, Chen Y, Matsumoto R, Kunieda T, Miyamoto S, Takahashi R, Lambon-Ralph MA, Ikeda A.
    • Organizer
      第38回日本神経科学学術大会
    • Place of Presentation
      神戸(Kobe)神戸コンベンションセンター
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 発作間欠期の徐波と高周波数律動(HFO)の共起:難治部分てんかん患者の皮質脳波の症例検討2015

    • Author(s)
      井上岳司、井内盛遠、松橋眞生、松本理器、人見健文、大封昌子、小林勝哉、金澤恭子、下竹昭寛、國枝武治、高橋良輔、池田昭夫
    • Organizer
      第17回日本ヒト脳機能マッピング学会
    • Place of Presentation
      大阪(毎日新聞社 オーバルホール)
    • Year and Date
      2015-07-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] 行為関連ネットワークの機能分化と症状の解明:皮質電気刺激による研究 Functional mapping of praxis network: Electrical cortical stimulation study.2015

    • Author(s)
      下竹昭寛、松本理器、小林勝哉、宇佐美清英、國枝武治、三國信啓、宮本亨、高橋良輔、池田昭夫
    • Organizer
      第9回Motor Control 研究会
    • Place of Presentation
      京都(京都大学)
    • Year and Date
      2015-06-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] Importance of actual recording of very low frequency EEG to evaluate VNS therapy of epilepsy: recovery filter could not augment effective signals.2015

    • Author(s)
      Borgil B, Matsuhashi M, Nakano N, Katagiri M, Kunieda T, Fumuro T, Shimotake A, Matsumoto R, Iida K, Kato A, Takahashi R, Ikeda A.
    • Organizer
      Neural Oscillation Conference 2015
    • Place of Presentation
      京都(京都大学百周年時計台記念館)
    • Year and Date
      2015-06-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] Functional connectivity revealed by Cortico-Cortical Evoked Potentials.2015

    • Author(s)
      Matsumoto R.
    • Organizer
      20th Korean Epilepsy Congress
    • Place of Presentation
      Gwangju, South Korea
    • Year and Date
      2015-06-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Network Disorders.2015

    • Author(s)
      Matsumoto R.
    • Organizer
      20th Korean Epilepsy Congress
    • Place of Presentation
      Gwangju, South Korea
    • Year and Date
      2015-06-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ヒト脳の機能可塑性:皮質電気刺激・外科的脳切除の観点から2015

    • Author(s)
      松本理器、國枝武治、池田昭夫
    • Organizer
      第30回日本生体磁気学会大会 シンポジウム2-3
    • Place of Presentation
      旭川(旭川市大雪クリスタルホール)
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Functional mapping of praxis network: Electrical cortical stimulation study.2015

    • Author(s)
      Shimotake A, Matsumoto R, Kobayashi K, Usami K, Kunieda T, Mikuni N, Miyamoto S, Takahashi R, Ikeda A.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] Long-term prognosis of smoldering autoimmune encephalitis.2015

    • Author(s)
      Matsumoto R, Kanazawa K, Togawa J, Hikiami R, Inoue T, Kobayashi K, Shimotake A, Sawamoto N, Takahashi R, Ikeda A.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高齢者のてんかん重積状態:臨床的特徴と予後因子について2015

    • Author(s)
      吉村 元、松本 理器、藤原 悟、上田 哲大、村瀬 翔、十河 正弥、石井 淳子、河野 智之、星 拓、藤堂 謙一、川本 未知、幸原 伸夫
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] Importance of very low frequency EEG to evaluate VNS therapy of epilepsy.2015

    • Author(s)
      Borgil B, Matsuhashi M, Nakano N, Iida K, Katagiri M, Shimotake A, Matsumoto R, Fumuro T, Kunieda T, Kato A, Takahashi R, Ikeda A.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] 皮質電気刺激によるヒト脳機能ネットワークの探索2015

    • Author(s)
      松本理器、山尾幸広、下竹昭寛、國枝武治、池田昭夫
    • Organizer
      第35回日本脳神経外科コングレス総会、第29回微小脳神経外科解剖研究会合同セッション:脳機能解剖の多次元解析
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2015-05-08
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 発作周辺期の徐波と高周波数律動(HFO)の共起:難治部分てんかん患者の皮質脳波の症例検討2014

    • Author(s)
      井上岳司、井内盛遠、松橋眞生、松本理器、人見健文、大封昌子、小林勝哉、金澤恭子、下竹昭寛、國枝武治、高橋良輔、池田昭夫
    • Organizer
      第44回日本臨床神経生理学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Research-status Report
  • [Presentation] 発作時DC電位の実際の記録・解析2014

    • Author(s)
      金澤恭子、松橋眞生、國枝武治、池田昭夫
    • Organizer
      第44回日本臨床神経生理学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] てんかん原性のバイオマーカー候補としての高周波律動(HFO):自発性および刺激誘発性HFOの現状と展望2014

    • Author(s)
      小林勝哉、松本理器、松橋眞生、國枝武治、池田昭夫
    • Organizer
      第44回日本臨床神経生理学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 皮質・白質電気刺激による高次脳機能ネットワークの術前マッピング2014

    • Author(s)
      下竹昭寛、松本理器、山尾幸広、國枝武治、池田昭夫
    • Organizer
      第44回日本臨床神経生理学会・学術大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Single Pulse Electrical Stimulation to Probe Human Brain Connectivity and Epileptogenicity2014

    • Author(s)
      Matsumoto R
    • Organizer
      Epilepsy Grand Round (by the George Washington University Epilepsy Center)
    • Place of Presentation
      Washington D.C. (USA)
    • Year and Date
      2014-11-18
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Functional connectivity of the human entorhinal cortex: a cortico-cortical evoked potential study2014

    • Author(s)
      Takeyama H, Matsumoto R, Kobayashi K, Usami K, Shimotake A, Kikuchi T, Kunieda T, Miyamoto S, Takahashi R, Ikeda A
    • Organizer
      Neuroscience 2014 (Society for Neuroscience annual meeting)
    • Place of Presentation
      Washington DC (USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Imaging Functional and Epileptic Networks with Cortical Stimulation2014

    • Author(s)
      Matsumoto R
    • Organizer
      7th International Workshop on Advances in Electrocorticography
    • Place of Presentation
      Washington D.C.(USA)
    • Year and Date
      2014-11-13 – 2014-11-14
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 前頭葉てんかんと睡眠異常 Frontal lobe epilepsy and sleep disorders2014

    • Author(s)
      松本理器、宇佐美清英、國枝武治、池田昭夫
    • Organizer
      第48回日本てんかん学会学術集会(東京)
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2014-10-02 – 2014-10-03
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Functional connectivity from the human entorhinal cortex: a corticocortical evoked potential study2014

    • Author(s)
      Takeyama H, Matsumoto R, Kobayashi K, Usami K, Shimotake A, Kikuchi T, Kunieda T, Miyamoto S, Takahashi R, Ikeda A
    • Organizer
      第37回日本神経科学学会Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Dynamic modulation of inter-areal neuronal integrity during sleep: direct evidence from high frequency activities induced by direct cortical stimulation in humans2014

    • Author(s)
      Usami K, Matsumoto R, Hitomi T, Kobayashi K, Shimotake A, Kikuchi T, Kunieda T, Mikuni N, Miyamoto S, Fukuyama H, Takahashi R, Ikeda A
    • Organizer
      第37回日本神経科学学会Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Slow cortical potential shift as a candidate marker for the efficacy of vagus nerve stimulation for seizure suppression2014

    • Author(s)
      Borgil B, Matsuhashi M, Nakano N, Iida K, Shimotake A, Matsumoto R, Fumuro T, Kunieda T, Kato A, Takahashi R, Ikeda A
    • Organizer
      第37回日本神経科学学会Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Intracranially-recorded ictal direct current shifts may precede high frequency oscillations in human epilepsy2014

    • Author(s)
      Kanazawa K, Matsumoto R, Imamura H, Matsuhashi M, Kikuchi T, Kunieda T, Mikuni N, Miyamoto S, Takahashi R, Ikeda A
    • Organizer
      第37回日本神経科学学会Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] ヒトてんかん病態での自発・誘発脳律動現象2014

    • Author(s)
      松本理器、國枝武治、池田昭夫
    • Organizer
      第37回日本神経科学学会Neuroscience 2014
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Reducing morbidity and mortality in the epilepsy monitoring unit2014

    • Author(s)
      Matsumoto R
    • Organizer
      第10回アジアオセアニアてんかん学会
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2014-08-07 – 2014-08-10
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Oscillatory response in CCEP2014

    • Author(s)
      Nakae T, Matsumoto R, Kunieda T, Matsuhashi M, Shimotake A, Usami K, Kobayashi K, Kikuchi T, Shibata S, Inano R, Nishida S, Fukuyama H, Ikeda A, Miyamoto S
    • Organizer
      Neural Oscillation Conference 2014
    • Place of Presentation
      岡崎コンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Subcortical network involved in gelastic seizure: an EEG-fMRI study2014

    • Author(s)
      Usami K, Matsumoto R, Sawamoto N, Murakami H, Inouchi M, Fumuro T, Shimotake A, Kato T, Mima T, Masuda H, Fukuyama H, Kameyama S, Takahashi R, Ikeda A
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-05-21 – 2014-05-24
    • Related Report
      2014 Research-status Report
  • [Book] Invasive Studies of the Human Epileptic Brain: Principles and Practice of Invasive Brain Recordings and Stimulation in Epilepsy: Chapter 36 Cortico-cortical evoked potential mapping (Section 5: Human Brain Mapping).2016

    • Author(s)
      Matsumoto R, Kunieda T.
    • Publisher
      Oxford University Press, London
    • Related Report
      2015 Annual Research Report
  • [Book] 神経内科シリーズ4、てんかん外来(辻貞俊編):診断に必要な検査.II外来診察の基本的な流れ2016

    • Author(s)
      吉村 元、松本理器
    • Total Pages
      232
    • Publisher
      メジカルビュー社
    • Related Report
      2015 Annual Research Report
  • [Book] ここが知りたい!臨床神経生理:意識障害2016

    • Author(s)
      十川純平、松本理器
    • Publisher
      中外医学社
    • Related Report
      2015 Annual Research Report
  • [Book] ここが知りたい!臨床神経生理:脳死.脳波2016

    • Author(s)
      大封昌子、松本理器
    • Publisher
      中外医学社
    • Related Report
      2015 Annual Research Report
  • [Book] 臨床てんかん学:5. 頭頂葉てんかん.D.年齢非依存性焦点性てんかん.第11章てんかんおよびてんかん類似症候群2015

    • Author(s)
      下竹昭寛、松本理器
    • Total Pages
      671
    • Publisher
      医学書院
    • Related Report
      2015 Annual Research Report
  • [Book] 臨床てんかん学:1. 側頭葉てんかん. D.年齢非依存性焦点性てんかん.第11章てんかんおよびてんかん類似症候群2015

    • Author(s)
      井内盛遠、松本理器
    • Total Pages
      671
    • Publisher
      医学書院
    • Related Report
      2015 Annual Research Report
  • [Book] 臨床てんかん学:2. 前頭葉てんかん(ジャクソン発作を除く).D.年齢非依存性焦点性てんかん.第11章てんかんおよびてんかん類似症候群2015

    • Author(s)
      宇佐美清英、松本理器
    • Total Pages
      671
    • Publisher
      医学書院
    • Related Report
      2015 Annual Research Report
  • [Book] 臨床てんかん学:4. Jackson発作関連てんかん.D.年齢非依存性焦点性てんかん.第11章てんかんおよびてんかん類似症候群2015

    • Author(s)
      芝田純也、松本理器
    • Total Pages
      671
    • Publisher
      医学書院
    • Related Report
      2015 Annual Research Report
  • [Book] 臨床てんかん学:3. 後頭葉てんかん.D.年齢非依存性焦点性てんかん.第11章てんかんおよびてんかん類似症候群2015

    • Author(s)
      金澤恭子、松本理器
    • Total Pages
      671
    • Publisher
      医学書院
    • Related Report
      2015 Annual Research Report
  • [Book] Invasive Studies of the Human Epileptic Brain: Principles and Practice of Invasive Brain Recordings and Stimulation in Epilepsy2015

    • Author(s)
      Matsumoto R, Kunieda T
    • Publisher
      Oxford University Press
    • Related Report
      2014 Research-status Report
  • [Book] 神経救急・脳神経外科周術期におけるてんかん発作の管理・ホスフェニトインによる実践集2015

    • Author(s)
      下竹昭寛、松本理器
    • Total Pages
      224
    • Publisher
      ライフ・サイエンス
    • Related Report
      2014 Research-status Report
  • [Book] 神経内科研修ノート2015

    • Author(s)
      井上岳司、松本理器、池田昭夫
    • Total Pages
      736
    • Publisher
      診断と治療社
    • Related Report
      2014 Research-status Report
  • [Book] 睡眠とてんかん その密接な関連性2015

    • Author(s)
      宇佐美清英、松本理器、池田昭夫
    • Total Pages
      103
    • Publisher
      ライフ・サイエンス
    • Related Report
      2014 Research-status Report
  • [Book] 臨床てんかん学2015

    • Author(s)
      金澤恭子、松本理器
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Book] 臨床てんかん学2015

    • Author(s)
      芝田純也、松本理器
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Book] 臨床てんかん学2015

    • Author(s)
      井内盛遠,松本理器
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Book] 脳神経外科医のための脳機能と局在診断2014

    • Author(s)
      松本理器
    • Total Pages
      348
    • Publisher
      文光堂
    • Related Report
      2014 Research-status Report
  • [Book] 症例から学ぶ戦略的てんかん診断・治療2014

    • Author(s)
      松本理器
    • Total Pages
      242
    • Publisher
      南山堂
    • Related Report
      2014 Research-status Report
  • [Book] てんかん専門医ガイドブック てんかんにかかわる医師のための基本知識2014

    • Author(s)
      松本理器
    • Total Pages
      320
    • Publisher
      診断と治療社
    • Related Report
      2014 Research-status Report
  • [Book] カンデル神経学(日本語翻訳版)2014

    • Author(s)
      山尾幸広、芝田純也、宇佐美清英、松本理器
    • Total Pages
      1696
    • Publisher
      メディカル・サイエンス・インターナショナル
    • Related Report
      2014 Research-status Report
  • [Remarks] 京都大学大学院医学研究科てんかん・運動異常生理学講座webpage(研究:日本語)

    • URL

      http://epilepsy.med.kyoto-u.ac.jp/research

    • Related Report
      2015 Annual Research Report
  • [Remarks] 京都大学大学院医学研究科てんかん・運動異常生理学講座webpage(研究:英語)

    • URL

      http://epilepsy.med.kyoto-u.ac.jp/research_en

    • Related Report
      2015 Annual Research Report
  • [Remarks] 京都大学大学院医学研究科てんかん・運動異常生理学

    • URL

      http://epilepsy.med.kyoto-u.ac.jp/results-3

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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