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Neural mechanisms of retrieval-induced forgetting in rats

Research Project

Project/Area Number 26590174
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionUniversity of Tsukuba

Principal Investigator

ICHITANI Yukio  筑波大学, 人間系, 教授 (80176289)

Co-Investigator(Kenkyū-buntansha) YAMADA Kazuo  筑波大学, 人間系, 准教授 (30282312)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords検索誘導性忘却 / 自発的物体再認 / ラット / グルタミン酸NMDA受容体 / アセチルコリン受容体 / 忘却
Outline of Final Research Achievements

The act of remembering can cause forgetting. Successful retrieval not only facilitates later recall of the retrieved items, but also impairs later recall of the related or competing items in memory. This memory phenomenon has been demonstrated with the retrieval-practice paradigm introduced by Anderson et al. (1994). In this study, we demonstrated the “retrieval-induced forgetting” phenomenon in a spontaneous object recognition test in rats. Additionally, administration of drugs which have detrimental effects on memory retrieval diminished the phenomenon.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (17 results)

All 2015 2014 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 4 results,  Open Access: 2 results) Presentation (7 results) (of which Int'l Joint Research: 2 results) Remarks (3 results)

  • [Journal Article] Hippocampal NMDA receptors are involved in rats’ spontaneous object recognition only under high memory load condition.2015

    • Author(s)
      Sugita, M., Yamada, K., Iguchi, N. & Ichitani, Y.
    • Journal Title

      Brain Research

      Volume: 1624 Pages: 370-379

    • DOI

      10.1016/j.bbr.2016.03.048

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Hippocampal AP5 treatment impairs both spatial working and reference memory in radial maze performance in rats.2015

    • Author(s)
      Yamada, K., Shimizu, M., Kawabe, K. & Ichitani, Y.
    • Journal Title

      European Journal of Pharmacology

      Volume: in press Pages: 137-141

    • DOI

      10.1016/j.ejphar.2015.03.080

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Latent inhibition in rats neonatally treated chronically with MK-801: Differential effects on conditioned taste aversion and conditioned emotional response.2015

    • Author(s)
      Niikura,R., Nozawa, T., Yamada,K., Kato, K. & Ichitani,Y.
    • Journal Title

      Behavioural Brain Research

      Volume: 283 Pages: 102-107

    • DOI

      10.1016/j.bbr.2015.01.029

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Latent inhibition in rats neonatally treated chronically with MK-801: differential effects on conditioned taste aversion and conditioned emotional response.2015

    • Author(s)
      Niikura, R., Nozawa, T., Yamada, K., Kato, K. & Ichitani, Y.
    • Journal Title

      Behavioural Brain Research

      Volume: 283 Pages: 102-107

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Tickling during adolescence alters fear-related and cognitive behaviors in rats after prolonged isolation.2014

    • Author(s)
      Hori, M., Yamada, K., Ohnishi, J., Sakamoto, S., Furuie, H., Murakami, K. & Ichitani, Y.
    • Journal Title

      Physiology & Behavior

      Volume: 131 Pages: 62-67

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Sleep deprivation impairs spontaneous object-place but not novel-object recognition in rats.2014

    • Author(s)
      Ishikawa, H., Yamada, K., Pavlides, C. & Ichitani, Y.
    • Journal Title

      Neuroscience Letters

      Volume: 580 Pages: 114-118

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Retrieval-induced forgetting in rats.2014

    • Author(s)
      Yamada, K., Ueno, M., Takano, E. & Ichitani, Y.
    • Journal Title

      Animal Cognition

      Volume: 17 Pages: 1407-1411

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Hippocampal NMDA receptors are involved in rats’ spontaneous object recognition only under high memory load condition.2015

    • Author(s)
      Yamada, K., Sugita, M. & Ichitani, Y.
    • Organizer
      Society for Neuroscience, 45th Annual Meeting
    • Place of Presentation
      Chicago, IL USA
    • Year and Date
      2015-10-21
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Scopolamine administered before retrieval diminishes retrieval-induced forgetting in spontaneous object recognition in rats.2015

    • Author(s)
      Ichikawa, A., Ichitani, Y. & Yamada, K.
    • Organizer
      日本動物心理学会第75回大会
    • Place of Presentation
      日本女子大学(東京都・文京区)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] Role of hippocampal NMDA receptors in the retrieval of spontaneous object recognition memory in rats.2015

    • Author(s)
      Takano, E., Yamada, K. & Ichitani, Y.
    • Organizer
      日本動物心理学会第75回大会
    • Place of Presentation
      日本女子大学(東京都・文京区)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] 新生仔期NMDA受容体遮断ラットの条件性味覚嫌悪における潜在制止に及ぼすDシクロセリンの効果2015

    • Author(s)
      新倉 怜・山田一夫・一谷幸男
    • Organizer
      第33回日本生理心理学会大会
    • Place of Presentation
      グランフロント大阪(大阪府・大阪市)
    • Year and Date
      2015-05-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] Sex differences in effects of infant odor memory on fear conditioning in adult rats.2015

    • Author(s)
      Ishikawa, H., Nakano, S., Ayabe-Kanamura, S., Ichitani, Y. & Yamada, K.
    • Organizer
      the AChems 37th Annual meeting
    • Place of Presentation
      Fort Myers, FL USA
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Retrieval-induced forgetting in rats' spontaneous object recognition.2014

    • Author(s)
      Yamada, K., Ueno, M., Takano, E. & Ichitani, Y.
    • Organizer
      44th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Washington, DC, USA.
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Effects of hippocampal administration of AMPA receptor antagonist NBQX on the retrieval of spontaneous object recognition memory.2014

    • Author(s)
      Takano, E., Yamada, K. & Ichitani, Y.
    • Organizer
      44th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Washington, DC, USA.
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Remarks] 筑波大学大学院 人間総合科学研究科 感性認知脳科学専攻 行動神経科学分野 一谷・山田グループ

    • URL

      http://www.kansei.tsukuba.ac.jp/~ichitanilab/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 筑波大学大学院人間総合科学研究科 感性認知脳科学専攻行動神経科学分野 一谷・山田グループ

    • URL

      http://www.kansei.tsukuba.ac.jp/~ichitanilab/

    • Related Report
      2014 Research-status Report
  • [Remarks] 筑波大学大学院人間総合科学研究科 感性認知脳科学専攻博士後期課程 行動神経科学分野

    • URL

      http://www.kansei.tsukuba.ac.jp/doctor/category/17/

    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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