Analysis of the mechanism of biological soliton by gene anaylysis
Project/Area Number |
26610129
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Biological physics/Chemical physics/Soft matter physics
|
Research Institution | University of Tsukuba |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | ソリトン / 孤立波(ソリトン) / 細胞集団運動 |
Outline of Final Research Achievements |
By the next generation DNA sequencer, we determined all the genome sequences of two soliton strains, KI-5 and KI-10, and their parental strain. By analysis of SNP, 75 genes of KI-5 and 75 genes of KI-10 were found to be changed. Furthermore, by deep-sequencing, 105 genes of KI-5 and 19 genes of KI-10 were found to increase during soliton. Next we tried to look up the responsible genes. Among those mutated genes, one gene was found to be related to soliton phenomenon by molecular biology technique.
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Report
(3 results)
Research Products
(6 results)