Regioselective activation of C-H bond using newly-designed metal complexes
| Project/Area Number |
26620077
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | Gakushuin University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | C-H結合 / カルベン / 炭素ｰ水素結合活性化 / 位置選択的 / C-H活性化 / 金属触媒 |
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| Outline of Final Research Achievements |
In this research, two types of C-H bond functionalization methodologies were explored.
The first one was the exploration of a new catalyst bearing a substrate capturing site for regioselective C-H bond activation. And it was found that newly-designed iridium-phenanthroline complex promoted meta-selective C-H borylation of mono-substituted benzenes, albeit chemical yields were not satisfactory.
The second approach was the utilization of photochemical isomerization of acylsilanes to siloxycarbenes for C-H insertion reaction and stereoselective cyclization of ortho-substituted benzoylsilanes was realized under photoirradiation conditions.
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Report
(3 results)
Research Products
(2 results)
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[Presentation] Intramolecular formal C-H insertion reaction of photochemically-generated siloxycarbenes leading to benzofused heterocycles2015
Author(s)
Nakada, Takuma, Ishii, Shuichi, Ishida, Kento, Iwasawa, Nobuharu, Kusama, Hiroyuki
Organizer
The International Chemical Congress of Pacific Basin Societies 2015
Place of Presentation
Honolulu, Hawaii, USA
Year and Date
2015-12-15
Related Report
Int'l Joint Research
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