Development of a bio-actuator by cell culture using collagen nanofibers
| Project/Area Number |
26630093
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
木村 建 信州大学, 学術研究院繊維学系, 教授 (20143993)
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| Research Collaborator |
SUZUKI Aya 信州大学, 繊維学部, 研究推進支援員
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | バイオアクチュエータ / 人工筋肉 / コラーゲン |
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| Outline of Final Research Achievements |
To aim at creating a cell culture bio-actuator capable of exhibiting superior characteristics such as biological muscle, we studied the establishment of the myoblasts orientation control technique and the research of the electrical stimulation condition of cultured muscle cells.
As a result, about half of myotube cells for the orientation of the sheets was able to orient parallel, by the orientation control experiment with the monolayer oriented collagen sheet. And also in the study of the electrical stimulation condition of the cultured muscle cells, we found that the amount of displacement of the contractile relaxation could controlled by an electrical stimulation condition using strong contraction and we established the basic technology to control the cell culture bio-actuator.
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Report
(4 results)
Research Products
(4 results)
