Project/Area Number |
26630094
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Intelligent mechanics/Mechanical systems
|
Research Institution | Nagoya University |
Principal Investigator |
ARAI Fumihito 名古屋大学, 工学(系)研究科(研究院), 教授 (90221051)
|
Co-Investigator(Kenkyū-buntansha) |
ICHIKAWA Akihiko 名城大学, 理工学部, 准教授 (20377823)
|
Project Period (FY) |
2014-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
|
Keywords | マイクロ・ナノデバイス / 超精密計測 / マイクロマシン / 機械力学・制御 / 細胞・組織 |
Outline of Final Research Achievements |
We conducted the research on a novel microrobot system, which enables to evaluate an anisotropy of viscoelastic property of embryo cells. Firstly, we developed the technique for transportation, positioning and rotation of embryo cells based on a vibration-induced flow on a microfluidic chip. Secondly, we integrated a miniaturized force sensor and on-chip robot to a microfluidic chip. We confirmed that the viscoelastic property of embryo cells could be evaluated by deforming the cells by the on-chip robot. We succeeded in transportation, positioning and 3D rotation of mouse oocytes on the chip by using the vibration-induced flow. Furthermore, we succeeded in a measurement of Young’s modulus of mouse oocytes by using the on-chip robot. Therefore, we succeeded to confirm the feasibility of basic principles of the microrobot system for the evaluation of anisotropy of viscoelastic property of embryo cells.
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