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Pad type drug delivery system using soft material

Research Project

Project/Area Number 26630095
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionNagoya University

Principal Investigator

Hata Seiichi  名古屋大学, 工学(系)研究科(研究院), 教授 (50293056)

Co-Investigator(Kenkyū-buntansha) MIZOSHIRI Mizue  名古屋大学, 大学院工学研究科, 助教 (70586594)
Co-Investigator(Renkei-kenkyūsha) ARAI Fumito  名古屋大学, 大学院工学研究科, 教授 (90221051)
SHIKIDA Mituhiro  名古屋大学, 大学院工学研究科, 准教授 (80273291)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywordsソフトメカニクス / 先進機械デバイス / マイクロマシン / MEMS / ドラッグデリバリーシステム / MEMS
Outline of Final Research Achievements

In this study, the following research was carried out, and the following results were obtained.
As the material of the flexible pad also serves as a drug solution tank, it was selected methylpolysiloxane (PDMS). microvalves using a photosensitive thermoresponsive gel was designed and fabricated. The fabricated pad type DDS (drug delivery system) as compared to the conventional micro-pump type DDS, demonstrated that low power consumption of about 1/10.
To confirm the principle of the proposed pad type DDS, the drug solution tank was applied with supposed contact pressure 20 kPa in daily life and the dose was measured at that time. From the measurement results, the DDS confirmed that it is possible to repeat dose of the expected. A single dose is approximately constant, it was confirmed that the administration time is within 1 minute.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2015 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Remarks (3 results)

  • [Journal Article] Reverse Lift-Off Process and Application for Cu-Zr-Ti Metallic Glass Thick Film Structures2015

    • Author(s)
      Shigetaka Watanebe, Junpei Sakurai, Mizue Mizoshiri, Seiichi Hata
    • Journal Title

      International Journal of Automation Technology

      Volume: 9 Issue: 6 Pages: 646-654

    • DOI

      10.20965/ijat.2015.p0646

    • NAID

      130007673922

    • ISSN
      1881-7629, 1883-8022
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] 新規ドラッグデリバリーシステムに用いるマイクロバルブの流量評価2015

    • Author(s)
      高桑暁,伊藤啓太郎,溝尻瑞枝,櫻井淳平,新井史人,秦 誠一
    • Organizer
      第1回日本機械学会イノベーション講演会
    • Place of Presentation
      広島大学
    • Year and Date
      2015-11-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] バイオレジストを用いたマイクロバルブの流量特性2015

    • Author(s)
      高桑暁,伊藤啓太郎,溝尻瑞枝,櫻井淳平,新井史人,秦 誠一
    • Organizer
      日本機械学会 2015年度年次大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2015-09-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] バイオレジストを用いたマイクロバルブの流量特性2015

    • Author(s)
      高桑 暁,伊藤 啓太郎,溝尻 瑞枝,桜井 淳平,新井 史人,秦 誠一
    • Organizer
      2015年度機械学会年次大会
    • Place of Presentation
      北海道大学工学部
    • Year and Date
      2015-09-13 – 2015-09-16
    • Related Report
      2014 Research-status Report
  • [Presentation] 金属系材料と新発想プロセスによるMEMS,マイクロデバイスの実現2015

    • Author(s)
      秦 誠一
    • Organizer
      第83回レーザ加工学会講演会
    • Place of Presentation
      大阪大学
    • Year and Date
      2015-06-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 金属系材料と高分子系材料融合を可能とする新しい積層加工技術2014

    • Author(s)
      秦 誠一
    • Organizer
      2014年度機械学会年次大会
    • Place of Presentation
      東京電機大学
    • Year and Date
      2014-09-07 – 2014-09-10
    • Related Report
      2014 Research-status Report
    • Invited
  • [Remarks] 名古屋大学大学院工学研究科 マイクロ・ナノプロセス工学研究グループ

    • URL

      http://mnp.mech.nagoya-u.ac.jp/jp/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 名古屋大学大学院工学研究科マイクロ・ナノシステム工学専攻 秦研究室

    • Related Report
      2014 Research-status Report
  • [Remarks] http://mnp.mech.nagoya-u.ac.jp/jp/

    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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