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New Concept of Virtual Reduction Mechanism and Apply for Cell Positioning with High Preciaison

Research Project

Project/Area Number 26630098
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionOsaka University

Principal Investigator

KANEKO MAKOTO  大阪大学, 工学(系)研究科(研究院), 教授 (70224607)

Project Period (FY) 2014-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywordsマイクロ流路 / 細胞マニピュレーション / 仮想減速器 / アクチュエータ / 能動的細胞制御 / マイクロチップ / マイクロ・ナノデバイス / システムオンチップ / バイオ関連機器 / ナノバイオ / 細胞・組織
Outline of Final Research Achievements

The finest manipulation resolution up to 250 nanometer is achieved with a macro-scale actuator in this research project. While the gigantic ratio difference between a macro-scale and a micro-scale fluidic system, a transmission system using PDMS deformation has been developed to make micro manipulation possible on a macro actuator. The research result directly benefits the cost and convenience of micro manipulation, and further, is currently applied on biomedical researches.

Report

(2 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (8 results)

All 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 3 results,  Open Access: 2 results) Presentation (5 results) (of which Invited: 1 results)

  • [Journal Article] On-Chip Actuation Transmitter for Enhancing the Dynamic Response of Cell Manipulation using a Macro-scale Pump2015

    • Author(s)
      T. Monzawa, M. Kaneko, C. Tsai, S. Sakuma, and F. Arai
    • Journal Title

      Biomicrofluidics

      Volume: 9 Issue: 1 Pages: 014114-014114

    • DOI

      10.1063/1.4907757

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] High Resolution Cell Positioning Based on a Flow Reduction Mechanism for Enhancing Deformability Mapping2015

    • Author(s)
      S. Sakuma, K. Kuroda, F. Arai, T. Taniguchi, T. Ohtani, Y. Sakata, and M. Kaneko
    • Journal Title

      Micromachines

      Volume: 5 Issue: 4 Pages: 1188-1201

    • DOI

      10.3390/mi5041188

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Geometrical Alignment for Improving Cell Evaluation in a Microchannel with Application on Multiple Myeloma Red Blood Cells2014

    • Author(s)
      C. Tsai, S. Sakuma, F. Arai, T. Taniguchi, T. Ohtani, Y. Sakata and M. Kaneko
    • Journal Title

      RSC Advances

      Volume: 4 Issue: 85 Pages: 45050-45058

    • DOI

      10.1039/c4ra08276a

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Cell Pinball: What is the Physics2015

    • Author(s)
      R. Murakami, M. Kaneko, S. Sakuma, and F. Arai
    • Organizer
      IEEE MEMS2015
    • Place of Presentation
      Portugal, Estril
    • Year and Date
      2015-01-18 – 2015-01-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] On-Chip Pressure sensing by Visualizing PDMS Deformation Using Microbeads2015

    • Author(s)
      C. Tsai and M. Kaneko
    • Organizer
      IEEE MEMS2015
    • Place of Presentation
      Portugal, Estril
    • Year and Date
      2015-01-18 – 2015-01-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Fluid Seperated Volumetric Flow Converter for High Speed and Precise Cell Position Contrl2015

    • Author(s)
      T. Monzawa, S. Sakuma, F. Arai, and F. Arai
    • Organizer
      IEEE MEMS2015
    • Place of Presentation
      Portugal, Estril
    • Year and Date
      2015-01-18 – 2015-01-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Evaluation of Cell Deformability through Fluidic Micro Channel2014

    • Author(s)
      M. Kaneko
    • Organizer
      URAI2014
    • Place of Presentation
      Malaysia, Kuala Lumpur
    • Year and Date
      2014-11-12 – 2014-11-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Cell Pinball2014

    • Author(s)
      R. Murakami, M. Kaneko, S. Sakuma, and F. Arai
    • Organizer
      IEEE MHS2015
    • Place of Presentation
      野依記念学術記念館(名古屋市千種区)
    • Year and Date
      2014-11-09 – 2014-11-12
    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2016-06-03  

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