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Development of autonomous drug delivery devices

Research Project

Project/Area Number 26630102
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionShibaura Institute of Technology

Principal Investigator

Maeda Shingo  芝浦工業大学, 工学部, 准教授 (40424808)

Co-Investigator(Kenkyū-buntansha) 長谷川 忠大  芝浦工業大学, 工学部, 教授 (10340605)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsゲル / ゲルアクチュエータ / ソフトアクチュエータ / ケミカルアクチュエータ / 自律駆動ゲル / ゲルポンプ / ポンプ
Outline of Final Research Achievements

The goal of this study is to develop autonomous drug delivery devices. We have prepared hydrogels coupled with oscillating chemical reaction, and then obtained hydrogels that are able to oscillate and generate peristaltic motion. Herein we try to apply the gels to devices that are capable of releasing chemicals periodically. We conducted reseaches on methodologies aboutj igs for gels, magnification of displacement in oscillating gels and work to exernal environment by oscillating gels in order to design the devices.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (16 results)

All 2017 2016 2015 2014

All Journal Article (7 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 7 results,  Open Access: 3 results,  Acknowledgement Compliant: 6 results) Presentation (9 results) (of which Invited: 2 results)

  • [Journal Article] Non-destructive ripeness assessment of apples using a non-contact laser excitation system based on a laser-induced plasma shock wave2017

    • Author(s)
      Hosoya, N., Mishima, M., Kajiwara, I. and Maeda, S.
    • Journal Title

      Postharvest Biology and Technology

      Volume: 128 Pages: 11-17

    • DOI

      10.1016/j.postharvbio.2017.01.014

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] High spatial and temporal resolution measurement of mechanical properties in hydrogels by non-contact laser excitation2016

    • Author(s)
      Naoki Hosoya, Yoshiki Terashima, Koh Umenai, and Shingo Maeda
    • Journal Title

      AIP Advances

      Volume: 6 Issue: 9 Pages: 11-17

    • DOI

      10.1063/1.4964305

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Large deformation of self-oscillating polymer gel2016

    • Author(s)
      Shingo Maeda, Terukazu Kato, Yuji Otsuka, Naoki Hosoya, Matteo Cianchetti, and Cecilia Laschi
    • Journal Title

      Physical Review E

      Volume: 93 Issue: 1 Pages: 010501-010501

    • DOI

      10.1103/physreve.93.010501

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Damage Detection in Transparent Materials Using Non-contact Laser Excitation by Nano-second Laser Ablation and High-speed Polarization-imaging Camera2016

    • Author(s)
      N. Hosoya, R. Umino, I. Kajiwara, S. Maeda, T. Onuma, T. Mihara
    • Journal Title

      Experimental Mechanics

      Volume: 56 Issue: 2 Pages: 339-343

    • DOI

      10.1007/s11340-015-0089-y

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Hemispherical breathing mode speaker using a dielectric elastomer actuator2015

    • Author(s)
      Naoki Hosoya, Shun Baba, and Shingo Maeda
    • Journal Title

      Journal of Acoustical Society of America

      Volume: 138 Issue: 4 Pages: EL424-EL428

    • DOI

      10.1121/1.4934550

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Thermo responsive hydrogel with porous structure2015

    • Author(s)
      S. Maeda, T. Kato, H. Kogure
    • Journal Title

      Applied Physics Letters

      Volume: in press

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Adhesion of Gels by silica particle2014

    • Author(s)
      H. Abe, Y. Hara, S. Maeda, S. Hashimoto
    • Journal Title

      J. Phys. Chem. B

      Volume: 118 Issue: 9 Pages: 2518-2522

    • DOI

      10.1021/jp410367v

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] アクティブに駆動する生体模倣型ゲルアクチュエータの創製2017

    • Author(s)
      前田真吾
    • Organizer
      日本機械学会バイオエンジニアリング部門 バイオサロン
    • Place of Presentation
      日本機械学会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Soft actuators driven by a chemical reaction network2016

    • Author(s)
      Shingo Maeda
    • Organizer
      Seminar in EPFL
    • Place of Presentation
      EPFL
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Design of self-moving gel driven by chemical energy2014

    • Author(s)
      R. Okada, T. Kogure, S. Nagasawa
    • Organizer
      IEEE ROBIO 2014
    • Place of Presentation
      Bali
    • Year and Date
      2014-11-05 – 2014-11-10
    • Related Report
      2014 Research-status Report
  • [Presentation] 化学エネルギーで駆動するポンプの設計2014

    • Author(s)
      高橋恒貴,長谷川忠大,山西陽子,前田真吾
    • Organizer
      第32回日本ロボット学会学術講演会
    • Place of Presentation
      九州産業大学
    • Year and Date
      2014-09-04 – 2014-09-06
    • Related Report
      2014 Research-status Report
  • [Presentation] 長軸方向に大変形する自励振動ゲルアクチュエータの設計2014

    • Author(s)
      加藤輝一,小暮輝,前田真吾
    • Organizer
      第32回日本ロボット学会学術講演会
    • Place of Presentation
      九州産業大学
    • Year and Date
      2014-09-04 – 2014-09-06
    • Related Report
      2014 Research-status Report
  • [Presentation] 中空状BZゲルに関する研究2014

    • Author(s)
      田辺圭,前田真吾
    • Organizer
      ROBOMEC2014
    • Place of Presentation
      富山市総合体育館
    • Year and Date
      2014-05-25 – 2014-05-29
    • Related Report
      2014 Research-status Report
  • [Presentation] ゲルモータの設計2014

    • Author(s)
      嶋本剛己,鈴木彩,木村敏樹,山西陽子,前田真吾
    • Organizer
      ROBOMEC2014
    • Place of Presentation
      富山市総合体育館
    • Year and Date
      2014-05-25 – 2014-05-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 界面張力差によって自走する高分子ゲルに関する研究2014

    • Author(s)
      小川拓,鈴木彩,木村敏樹,前田真吾
    • Organizer
      ROBOMEC2014
    • Place of Presentation
      富山市総合体育館
    • Year and Date
      2014-05-25 – 2014-05-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 自走する高分子ゲルの設計2014

    • Author(s)
      岡田怜也,前田真吾
    • Organizer
      ROBOMEC2014
    • Place of Presentation
      富山市総合体育館
    • Year and Date
      2014-05-25 – 2014-05-29
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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