Elucidation of the waterborne virus inactivation mechanism during drinking water disinfection processes by using a novel method based on mass spectrometry
| Project/Area Number |
26630242
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Civil and environmental engineering
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 水系感染症 / 水系感染症ウイルス / 精密質量分析 / タンパク質 / ペプチド / 消毒処理 / 不活化メカニズム / アデノウイルス / 大腸菌ファージ / カプシドタンパク質 / コアタンパク質 / ノロウイルス |
|---|
| Outline of Final Research Achievements |
The objective of this study was to elucidate the waterborne virus inactivation mechanism during drinking water disinfection processes by using a novel method applying mass spectrometry. As a result, chemical oxidation in the virus capsid protein by OH radical was observed after UV254-H2O2 process and oxidized peptides of virus capsid protein were successfully identified by using the novel method based on mass spectrometry.
|
Report
(3 results)
Research Products
(6 results)
-
-
-
-
-
[Presentation] 腸管アデノウイルスの凝集処理性2014
Author(s)
村井一真, 白崎伸隆, 松井佳彦, 松下拓
Organizer
平成26年度全国会議 (水道研究発表会)
Place of Presentation
ポートメッセなごや, 愛知県名古屋市
Year and Date
2014-10-31
Related Report
-
[Presentation] Development of novel high-basicity polyaluminum chloride for effective virus removal2014
Author(s)
Marubayashi, T., Shirasaki, N., Matsushita, T., Matsui, Y. and Oshiba, A.
Organizer
IWA World Water Congress and Exhibition
Place of Presentation
Lisbon Congress Centre, Lisbon, Portugal
Year and Date
2014-09-23
Related Report
