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Synthesis of a novel antiviral powder material and understanding of the mechanism for improvement of durability of antiviral activities

Research Project

Project/Area Number 26630317
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Inorganic materials/Physical properties
Research InstitutionTottori University

Principal Investigator

Chen Zhong-Chun  鳥取大学, 工学(系)研究科(研究院), 教授 (00282111)

Co-Investigator(Renkei-kenkyūsha) ONDA Tetsuhiko  鳥取大学, 工学研究科, 准教授 (80273879)
AKAO Takahiro  鳥取大学, 工学研究科, 助教 (70335503)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords抗ウイルス材料 / メカニカルアロイング / 酸化カルシウム / アルミナ / ジルコニア / 鳥インフルエンザ / セラミックス / 公害防止・対策 / 水酸化カルシウム
Outline of Final Research Achievements

We have successfully developed a novel antiviral powder material consisting of calcium oxide and small amounts of alumina or zirconia as a second phase. The composite powders were synthesized by mechanical alloying (MA). The effects of alumina or zirconia addition and MA conditions on antiviral activities of calcium oxide have been investigated against H5N3 avian influenza virus. The incorporation of small amounts of alumina or zirconia significantly improved the durability of antiviral activities of MAed and hydrated calcium oxide. The reasons for improvement of durability of antiviral activities seem to be attributed to the solid solution of alumina or zirconia into calcium oxide and agglomeration of the powders during the mechanical alloying.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (4 results)

All 2016 2015

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Preparation of a Novel Antiviral Material by Mechanical Milling2016

    • Author(s)
      Tetsuhiko Onda, Yusuke Yoneda, Takahiko Akao, Koichi Motoike, Hiroshi Ito, Toshihiro Ito and Zhong-Chun Chen
    • Journal Title

      Journal of the Japan Society of Powder and Powder Metallurgy

      Volume: 63

    • NAID

      130005164654

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Preparation of a Novel Antiviral Material by Mechanical Milling2015

    • Author(s)
      Tetsuhiko Onda, Yusuke Yoneda, Takahiko Akao, Koichi Motoike, Hiroshi Ito, Toshihiro Ito and Zhong-Chun Chen
    • Organizer
      The 3rd International Conference on Powder Metallurgy in Asia
    • Place of Presentation
      Kyoto
    • Year and Date
      2015-11-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 抗ウイルス性粉体材料の耐久性に及ぼすメカニカルミリングとジルコニア添加の影響2015

    • Author(s)
      松本賢樹,酒井颯太,赤尾尚洋,音田哲彦,陳中春
    • Organizer
      平成27年日本鉄鋼協会・日本金属学会中国四国支部講演大会
    • Place of Presentation
      広島市
    • Year and Date
      2015-08-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] メカニカルミリングを利用した新規抗ウイルス材料創製のための基礎研究2015

    • Author(s)
      音田哲彦、米田祐介、赤尾尚洋、本池紘一 、伊藤啓史、伊藤壽啓 、陳中春
    • Organizer
      日本金属学会2015年春季講演大会
    • Place of Presentation
      東京大学駒場 I 地区キャンパス
    • Year and Date
      2015-03-19
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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