| Project/Area Number |
26630345
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Structural/Functional materials
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
Kuroda Kensuke 名古屋大学, 未来材料・システム研究所, 准教授 (00283408)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HIBI Hideharu 名古屋大学, 医学系研究科, 教授 (90345885)
TSUCHIYA Shuhei 名古屋大学, 医学部附属病院, 助教 (20569785)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 生体材料 / 組織適合性 / 表面吸着 / タンパク質 / チタン / アルミナ / ジルコニア / ＰＥＥＫ / 薬剤 |
|---|
| Outline of Final Research Achievements |
We developed the formation technique for “Bioimplants”, integrating medical experiences into engineering techniques. It is important to produce the hydrophilic surface in order to adsorb the several kinds of protein on the metallic, ceramics, and polymer implants. In this research, we found hydro-techniques for the super-hydrophilicity of these implants and for keeping the super-hydrophilicity. Several kinds of protein were adsorbed on the super-hydrophilic implants surfaces (bioimplant). Important proteins were found for the improvement of the osteoconductivity by the implantation of the protein-adsorbed samples in rats’ tibia.
|
