| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
How multiple neural signaling is discriminate and crosstalk in the neuron is important question. Here we established experimental system for analyzing their processing of multiple neural signaling. We found that a sensoryneuron known as pheromone and light sensing-neuron acts as a thermosensoryneuron. In this multi stimuli common sensoryneuron, trimeric G protein, our culcium imaging revealed that guanylyl cyclase and phosphodiesterase regulates pheromone, light and temperature signaling. However, we found that GPA-1 encoding G protein alpha subunit and PDE-3 encoding phosphodiesterase control temperature signaling specifically. These results suggest that commonalities and differences in the molecular components concerned with pheromone, light and temperature signaling in a single sensory neuron.
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