| Project/Area Number |
26640062
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory animal science
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| Research Institution | Nara Medical University |
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Principal Investigator |
Horie Kyoji 奈良県立医科大学, 医学部, 教授 (30333446)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 遺伝学 / ゲノム / 再生医学 / バイオテクノロジー / 発生・分化 / 遺伝子 / ゲノム編集 / CRISPR / ES細胞 |
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| Outline of Final Research Achievements |
We have established an experimental system to efficiently elucidate gene functions by introducing gene mutations in a genome-wide manner. We utilized mouse ES cells as a model system. ES cells and iPS cells are drawing attentions as a promising tool for regenerative medicine. Another useful aspect of ES cells and iPS cells is that they provide excellent experimental protocols for the investigation of cell lineage determination. The method established in the present study will be applicable in various fields of life science.
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