Exploration of biological rhythms for temperature compensation

• Project/Area Number: 26650121
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Animal physiology/Animal behavior
• Research Institution: Kyushu University
• Principal Investigator: Ito Hiroshi 九州大学, 芸術工学研究科(研究院), 助教 (20512627)
• Co-Investigator(Kenkyū-buntansha): KOUZUMA Takiko 九州大学, 芸術工学研究院, 教務職員 (70274545)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 生物リズム / 温度補償性 / イカ / 色素胞 / ケンサキイカ / 概日リズム

Outline of Final Research Achievements

Biological phenomena with a 24 hours period is called circadian rhythms. Although Biochemical reactions generally depend on temperature, the period of circadian rhythms do not depend on temperature. This property is called "temperature compensation" and it is shared among circadian rhythms of any organisms. In this research, I explored temperature compensation of biological rhythms except circadian rhythms.
I focused contraction rhythms of squid and examined its period under various temperatures. The weaker temperature compensation compared with circadian rhythms was observed through this project.

Research Products

• [Int'l Joint Research] ジョセフフーリエ大学(フランス)
• [Journal Article] Effect of Multiple clock gene ablations on the circadian period-length and temperature compensation in mammalian cells. (2016)
  • Author(s): Tsuchiya Y., Umemura Y., Minami Y., Koike N., Hosokawa T., Hara M., Ito H., Inokawa H. & Yagita K.
  • Journal Title: Journal of Biological Rhythms Volume: 31 Issue: 1 Pages: 48-56
  • DOI: 10.1177/0748730415613888
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Discrete and ultradiscrete models for biological rhythms comprising a simple negative feedback loop (2015)
  • Author(s): Gibo S, Ito H
  • Journal Title: Journal of Theoretical Biology Volume: 378 Pages: 89-95
  • DOI: 10.1016/j.jtbi.2015.04.024
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Vection is unaffected by circadian rhythm (2015)
  • Author(s): Ogawa Y, Ito H, Seno T
  • Journal Title: Psychology Volume: 6 Issue: 04 Pages: 440-446
  • DOI: 10.4236/psych.2015.64041
  • Peer Reviewed / Open Access
• [Journal Article] Equilibrium frequency of endosymbionts in multiple infections based on the balance between vertical transmission and cytoplasmic incompatibility (2014)
  • Author(s): Kawasaki, Y., Ito, H. and Kajimura, H.
  • Journal Title: PLoS ONE Volume: 9 Issue: 4 Pages: 94900-94900
  • DOI: 10.1371/journal.pone.0094900
  • Peer Reviewed / Open Access
• [Presentation] ケンサキイカ色素胞収縮リズムの温度依存性 (2015)
  • Author(s): 伊藤浩史
  • Organizer: 頭足類学を紡ぐ
  • Place of Presentation: 沖縄
  • Year and Date: 2015-07-31
  • Invited
• [Presentation] 生物リズムの制御：光・温度・電気 (2015)
  • Author(s): 伊藤浩史
  • Organizer: 九州山口リズム研究会
  • Place of Presentation: 鹿児島大学
  • Year and Date: 2015-03-06 – 2015-03-07
• [Presentation] 生物リズムと温度 (2014)
  • Author(s): 伊藤浩史
  • Organizer: 時間生物学会
  • Place of Presentation: 九州大学
  • Year and Date: 2014-11-07 – 2014-11-09
• [Book] 生物時計の生態学—リズムを刻む生物の世界 (2015)
  • Author(s): 伊藤浩史
  • Total Pages: 260
  • Publisher: 文一総合出版
• [Book] Dynamics of Circadian Oscillation in the SCN (2014)
  • Author(s): Hiroshi Ito
  • Total Pages: 350
  • Publisher: Hokkaido Univ. Press
• [Remarks] 伊藤浩史 website
  • URL: http://www.design.kyushu-u.ac.jp/~hito/
• [Remarks] 研究者HP
  • URL: http://www.design.kyushu-u.ac.jp/~hito/