| Project/Area Number |
26660213
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal production science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI IKUO 宮崎大学, 農学部, 准教授 (20576293)
NAKAHARA KEIKO 宮崎大学, 農学部, 准教授 (90315359)
KITAHARA GOU 宮崎大学, 農学部, 助教 (90523415)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | トランスレーショナルリサーチ / グレリン / デスアシルグレリン / 熱中症 / 体温 / 体温調節中枢 / 体温低下作用 |
|---|
| Outline of Final Research Achievements |
The heat stroke in domestic animals under the high temperature of the summer causes the economic damage. We found that treatment with desacyl ghrelin reduced body temperature in rats. Therefore we examined whether desacyl ghrelin prevent the heat stroke in beef cattle and dairy cattle at the high temperature of the summer, and observed an effect of the prevention of heat stroke. In addition, in a rat experiment, treatment with desacyl ghrelin improved normally the incremental change (creatinine, urea nitrogen and hematocrit etc.) of the blood property under the high temperature. These results suggest that desacyl ghrelin may be effective for the heat stroke prevention.
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