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Why the ipsilateral relationship where first follicular wave dominant follicle and corpus luteum are present in the same ovary decrease fertility in cattle?

Research Project

Project/Area Number 26660234
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionObihiro University of Agriculture and Veterinary Medicine

Principal Investigator

MATSUI MOTOZUMI  帯広畜産大学, 畜産学部, 教授 (20374762)

Co-Investigator(Kenkyū-buntansha) 羽田 真悟  帯広畜産大学, 畜産学部, 助教 (40553441)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords卵巣 / 黄体 / 卵胞 / 受胎性 / 乳牛 / 第一卵胞波 / 第一卵胞波主席卵胞 / 共存・非共存 / 受胎率
Outline of Final Research Achievements

The effects of the locational relationship between the first follicular wave dominant follicle (W1DF) and the corpus luteum (CL) on fertility after insemination were examined in dairy cattle. In the ipsilateral relationship where W1DF and CL are present in the same ovary, the conception rate was significantly lower than that in the contralateral relationship where W1DF and CL are exist in different ovaries. In the contralateral relationship, the concentration of progesterone (P4) in the blood and endometrial tissues at the early stage after ovulation was higher, and the mRNA expression of P4 receptor (PGRMC2) was higher in the ipsilateral relationship. Therefore, the positional relationship between W1DF and CL may regulate P4 concentration and expression of P4 receptor in the endometrium, and then affect fertility. Since hormonal treatments changed the positional relationship between W1DF and CL, the positional relationship might be regulated artificially.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014

All Journal Article (5 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results,  Acknowledgement Compliant: 5 results) Presentation (8 results) (of which Invited: 1 results)

  • [Journal Article] Differences in progesterone concentrations and mRNA expressions of progesterone receptors in bovine endometrial tissue between the uterine horns ipsilateral and contralateral to the corpus luteum2016

    • Author(s)
      Takahashi H, Haneda S, Kayano M, Matsui M.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 78 Issue: 4 Pages: 613-618

    • DOI

      10.1292/jvms.15-0366

    • NAID

      130007331494

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 排卵後の第1卵胞ウェーブ主席卵胞と黄体との位置関係が人工授精後の受胎率に及ぼす影響に関する研究2015

    • Author(s)
      三浦亮太朗、松井基純
    • Journal Title

      繁殖技術

      Volume: 35 Pages: 22-25

    • NAID

      40020583144

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] 授精後5日目のhCG投与時における第1卵胞波主席卵胞波と黄体との位置関係が受胎率に及ぼす影響.2015

    • Author(s)
      吉岡乃生、三浦亮太朗、羽田真悟、松井基純
    • Journal Title

      繁殖技術

      Volume: 35 Pages: 37-38

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Ovulation of the preovulatory follicle originating from the first-wave dominant follicle leads to formation of an active corpus luteum2015

    • Author(s)
      Miura R, Haneda S, Matsui M.
    • Journal Title

      Journal of Reproduction and Development

      Volume: 61 Issue: 4 Pages: 317-323

    • DOI

      10.1262/jrd.2014-099

    • NAID

      130005094654

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Development of the first follicular wave dominant follicle on the ovary ipsilateral to the corpus luteum is associated with decreased conception rate in dairy cattle.2015

    • Author(s)
      Miura R, Haneda S, Kayano M, Matsui M
    • Journal Title

      Journal of Dairy Science

      Volume: 98 Issue: 1 Pages: 318-321

    • DOI

      10.3168/jds.2014-8388

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] ウシ人工授精後の第一卵胞波主席卵胞と黄体の位置関係が卵胞および黄体の機能と受胎率に 及ぼす影響2016

    • Author(s)
      硲野 健、服部 昌大、三浦 亮太朗、高橋 啓人、羽田 真悟、松井 基純
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学(神奈川県藤沢市)
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 卵胞の発育に影響をおよぼす卵巣内局所の要因2016

    • Author(s)
      三浦亮太郎
    • Organizer
      平成27年度日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      秋田キャッスルホテル(秋田県・秋田市)
    • Year and Date
      2016-02-26
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 交雑種雌牛への受精卵移植前のP4濃度と黄体および第1卵胞波卵胞の直径が受胎性に及ぼす影響について2015

    • Author(s)
      高橋啓人, 三浦亮太朗, 武富敏郎, 羽田真悟, 松井基純
    • Organizer
      第66回北海道地区三学会(日本産業動物獣医学会)
    • Place of Presentation
      酪農学園大学(北海道・江別市)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Research-status Report
  • [Presentation] 授精後5日目のhCG投与時における第1卵胞波主席卵胞と黄体との位置関係が受胎率に及ぼす影響2014

    • Author(s)
      吉岡乃生、三浦亮太朗、羽田真悟、松井基純
    • Organizer
      第70回北海道家畜人工授精技術研修記念大会
    • Place of Presentation
      さっぽろ芸術文化の館
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 乳用経産牛における第一卵胞波主席卵胞と黄体の位置関係が受胎率および産子の性別に及ぼす影響2014

    • Author(s)
      古山敬祐、小山毅、松井義貴、大坂郁夫、草刈直仁、三浦亮太朗、松井基純
    • Organizer
      第65回北海道地区三学会(産業動物獣医学会北海道地区学会)
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-11 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] ウシにおける同一卵巣内での第1卵胞波主席卵胞と黄体との共存が主席卵胞の発育に与える影響2014

    • Author(s)
      三浦亮太朗、吉岡乃生、羽田真悟、松井基純
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Dose the ipsilateral location of the first wave dominant follicle and corpus luteum affect conception rate in cattle?2014

    • Author(s)
      Miura R., Haneda S., Kayano K. and Matsui M
    • Organizer
      Ninth International Symposium on Reproduction in Domestic Ruminants
    • Place of Presentation
      Hotel Nikko Northland Obihiro
    • Year and Date
      2014-08-25 – 2014-08-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 黄体が同一卵巣内に共存する第1卵胞波主席卵胞に及ぼす影響2014

    • Author(s)
      三浦亮太朗、吉岡乃生、羽田真悟、松井基純
    • Organizer
      第107回日本繁殖生物学会
    • Place of Presentation
      帯広畜産大学
    • Year and Date
      2014-08-21 – 2014-08-24
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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