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Development of low invasive radio-induced hyperthermia against the deep part tumor

Research Project

Project/Area Number 26660240
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionTottori University

Principal Investigator

OKAMOTO Yoshiharu  鳥取大学, 農学部, 教授 (50194410)

Co-Investigator(Kenkyū-buntansha) TAMURA yutaka  千葉大学, 大学院医学研究院, 准教授 (50263174)
AWAZU Kunio  大阪大学, 大学院工学研究科, 教授 (30324817)
ASANUMA Taketoshi  宮崎大学, 農学部, 教授 (40332473)
SUGIYAMA Masahiko  鳥取大学, 農学部, 准教授 (00432609)
Co-Investigator(Renkei-kenkyūsha) OSAKI Tomohiro  鳥取大学, 農学部, 准教授 (40431332)
TSUKA Takeshi  鳥取大学, 農学部, 准教授 (30432610)
AZUMA Kazuo  鳥取大学, 農学部, 准教授 (50721841)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsがん / 温熱療法 / ラジオ波 / 胎児 / 自然発症動物 / 犬猫 / 腫瘍 / 生体深部
Outline of Final Research Achievements

In the present study, we recognized onchothermia heat selectively tumor tissue. In vivo study using pregnant rat, it was found that onchothermia did not have effect on organogesis of the brain. In addition, it was found that onchothermia induced apoptosis in mouse model. Furthermore, it was found that onchothermia did not decrease the volume of the animal spontaneous tumors. However, by combination of low dose chemotherapy, this therapy became to be effective for the tumors.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] 獣医領域でのオンコサーミアの使用2015

    • Author(s)
      岡本芳晴、アンドチ・ガボール、東 和生、大崎智弘、伊藤典彦、村端悠介、柄 武士、今川智敬
    • Organizer
      オンコサーミア研究会
    • Place of Presentation
      富山
    • Year and Date
      2015-10-18
    • Related Report
      2015 Annual Research Report

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Published: 2014-04-04   Modified: 2017-05-22  

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