Identification of genes causing canine breed differences in disease susceptibility by a new analysis method
| Project/Area Number |
26660244
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
MOMOZAWA Yukihide 独立行政法人理化学研究所, 統合生命医科学研究センター, 研究員 (40708583)
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| Project Period (FY) |
2014-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | イヌ / ゲノム / 疾患 / 犬種差 / SNP / 統計 |
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| Outline of Final Research Achievements |
It is very important for veterinary medicine to identify genetic variants associated with disease risk. For this purpose, we developed a new method focusing on breed differences in disease susceptibility. We also collected frequency information of genetic variants over canine whole genome in 40 breeds and disease susceptibility of each breed for 80 diseases. Finally, we applied the new method to these dataset and newly identified eight genome wide significant associations between genetic variants and disease susceptibility.
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Report
(2 results)
Research Products
(2 results)
