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Study for development of elastic silk

Research Project

Project/Area Number 26660265
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Insect science
Research InstitutionShinshu University

Principal Investigator

TAMADA Yasushi  信州大学, 学術研究院繊維学系, 教授 (70370666)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsシルク弾性率制御 / シルク繊維 / ペプチド / 引っ張り試験 / 細胞培養 / QCM / エレクトロスピニング
Outline of Final Research Achievements

Some disturbing molecules, which are to inhibit the formation of the crystal structure in silk fibroin fiber, were designed and synthesized for controlling the modulus of silk fiber in order to use the silk fibroin materials in tissue engineering field as the cell scaffold for soft tissue reconstitution.A novel peptide, RP3R-15, was able to decrease the tensile modulus of the electrospun fibroin nano-fiber non-woven mat. A single fiber of several transgenic fibroins which are contained the crystal regions with various length and number were evaluated the tensile and compressive modulus. However no effects were observed in this study.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (2 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results)

  • [Journal Article] Production of three-dimensuonal silk fibroin nanofiber non-woven fabric by wet electrospinning2017

    • Author(s)
      Kishimoto Y, Kobashi T, Morikawa H, Tamada Y
    • Journal Title

      J. Silk Sci. Tech. Jpn.

      Volume: 25 Pages: 49-57

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] フィブロイン由来ペプチドによるシルク改変の試み2017

    • Author(s)
      稲垣まり子、小橋尚教、玉田靖
    • Organizer
      第64回日本シルク学会発表会
    • Place of Presentation
      つくばイノベーションプラザ、つくば
    • Year and Date
      2017-05-18
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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