Development of the detection method of pharmacogenomic SNP using nucleic acid chromatography
| Project/Area Number |
26670071
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Medical pharmacy
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 一塩基多型 / 薬剤反応性 / 核酸クロマトグラフィー / 遺伝子診断法 |
|---|
| Outline of Final Research Achievements |
It is now apparent that some reactions such as drug effect and adverse reactions are strongly influenced by single nucleotide polymorphisms (SNP) such as drug metabolizing enzymes. So we are now aiming to construct a device (nucleic acid chromatography strip) able to detect the SNP of patient’s drug responsive genes quickly and easily at the bedside or in the clinical sites. Genotypes can be detected with a single strip by reading the location where the blue line was detected on the strip.
|
Report
(3 results)
Research Products
(1 results)
