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Construction of controlled insulin release system using functional thin films and its development to innovative DDS

Research Project

Project/Area Number 26670083
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical pharmacy
Research InstitutionOhu University

Principal Investigator

Ono Tetsuya  奥羽大学, 薬学部, 講師 (70433555)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords電気化学 / 電解触媒反応 / 機能性物質 / 電解重合法 / 機能性薄膜
Outline of Final Research Achievements

We investigate the electrocatalytic activity of the TEMPO-modified electrode for the oxidation of carbohydrates in phosphate buffer solution under neutral aqueous solution. The modified electrode was prepared onto the surface of a glassy carbon electrode by the electrochemical polymerization of TEMPO precursor containing pyrrole side chain. Cyclic voltammetric studies showed that the anodic peak current of the cyclic voltammogram increased in the concentration of carbohydrates in a dose-dependent manner. On the other hand, in the CVs of the homogeneous TEMPO in the presence of carbohydrates, the oxidation peaks did not increase dramatically.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (6 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (5 results)

  • [Journal Article] Electrochemical Determination of D-Glucose Using Nortropine-N-Oxyl under Physiological Conditions2015

    • Author(s)
      Katsuhiko Sato, Tetsuya Ono, Kentaro Yoshida, Toshinori Ito, Yoshitomo Kashiwagi
    • Journal Title

      Electroanalysis

      Volume: 27 Pages: 2272-2274

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] ニトロキシルラジカル修飾電極を用いた糖アルコールの水溶媒系電解触媒酸化反応2016

    • Author(s)
      清水 駿生、小野 哲也、吉田 健太郎、柏木 良友
    • Organizer
      第55回日本薬学会東北支部大会
    • Place of Presentation
      奥羽大学
    • Year and Date
      2016-09-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] ノルトロピン型ニトロキシルラジカルを用いたアミン類の電気化学分析2016

    • Author(s)
      小野 哲也、和泉 かおる、佐藤 勝彦、吉田 健太郎、柏木 良友
    • Organizer
      日本分析化学会第65年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2016-09-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] アミン類の中性水溶媒系電解触媒酸化反応2016

    • Author(s)
      和泉かおる、小野哲也、佐藤勝彦、吉田健太郎、柏木良友
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Research-status Report
  • [Presentation] ニトロキシルラジカル修飾電極を用いた糖アルコールの水溶媒系電解触媒酸化反応2016

    • Author(s)
      清水駿生、小野哲也、吉田健太郎、柏木良友
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Research-status Report
  • [Presentation] 重合単量体構造設計による電解重合複素環ポリマーの作製制御2014

    • Author(s)
      小笠原陵、小野哲也、佐藤くるみ、吉田健太郎、柏木良友
    • Organizer
      第44回複素環化学討論会
    • Place of Presentation
      札幌市民ホール
    • Year and Date
      2014-09-10 – 2014-09-12
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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