Development of the measuring technique of ATP dynamics in beating whole heart
| Project/Area Number |
26670100
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General physiology
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| Research Institution | Kyoto University (2015)
Gunma University (2014) |
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Principal Investigator |
yamamoto masamichi 京都大学, 医学(系)研究科(研究院), 特任講師 (70423150)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | アデノシン三リン酸 / 心臓 |
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| Outline of Final Research Achievements |
In 2009, it was reported that the distribution of ATP dynamics in culture cell by ATeam, which was developed for FRET probe detecting ATP levels in vivo. In this study, I tried to develop novel ATeam which measure the correct ATP levels for high resolution and high speed, then was successful in developing the powerful mouse measuring the ATP dynamics in mouse. I tried to examine the ATP dynamics in beating heart under the fluorescent microscope. At the result, it was clear that ATP levels are dependent on beating in heart.
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Report
(3 results)
Research Products
(4 results)
