Research Project
Grant-in-Aid for Challenging Exploratory Research
Protein S-polythiolation is a post-translational modification that introduce additional sulfur atoms on cysteine residues in proteins. We developed specific method that enables biotin-labeling on S-polythiolated cysteines by using methylsulfonyl benzothiazole and cyanide biotin. We successfully identified endogenous S-polythiolated proteins including cytoskeleton proteins. The method we developed may help further understanding of signal transduction mediated via protein S-polythiolation.
All 2016 2015 2014 Other
All Journal Article (10 results) (of which Int'l Joint Research: 1 results, Peer Reviewed: 8 results, Open Access: 5 results, Acknowledgement Compliant: 3 results) Presentation (13 results) (of which Invited: 3 results) Remarks (2 results)
Biochemistry
Volume: 55 Issue: 5 Pages: 751-761
10.1021/acs.biochem.5b00774
ACS Chemical Neuroscience
Volume: 6 Issue: 10 Pages: 1715-1725
10.1021/acschemneuro.5b00196
Plant Cell Physiol.
Volume: 56 Issue: 8 Pages: 1481-1489
10.1093/pcp/pcv069
Chem Res Toxicol.
Volume: 印刷中 Issue: 5 Pages: 838-847
10.1021/tx500416y
細胞工学
Volume: 34 Pages: 392-395
臨床と微生物
Volume: 42 Pages: 177-182
Proc. Natl. Acad. Sci. USA
Volume: (印刷中) Issue: 21 Pages: 7606-7611
10.1073/pnas.1321232111
Free Radic. Biol. Med.
Volume: 77 Pages: 82-94
10.1016/j.freeradbiomed.2014.09.007
感染・炎症・免疫
Volume: 44 Pages: 16-21
http://kumadai-bisei.com/
http://kumadai-bisei.com