Analysis for microRNA in osteo- and chondro-sarcomas
Project/Area Number |
26670179
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Human pathology
|
Research Institution | Iwate Medical University |
Principal Investigator |
Satoh Takashi 岩手医科大学, 医学部, 教授 (20170756)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 転移 / 骨軟部腫瘍 / miRNA / lincRNA / ARF6 / polycome / PC2 / ChIP-sequence |
Outline of Final Research Achievements |
Advances in treatment modalities for osteo-, and chondro-sarcomas (OCSs)contributes to their disease outcomes, whereas these have been still unsatisfactory in metastatic tumors of OCS. We identified overexpression of lincRNA-ARF6 OCSs cell lines with high metastatic potentiality. The lincRNA-ARF6 regulated ARF6 expression, but not related with motility and invasion of these cell lines. Further studies will be needed for contribution of non-coding RNA in OCSs metastasis.
|
Report
(4 results)
Research Products
(3 results)
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[Journal Article] Neural cell adhesion molecule (CD56)-positive B cell lymphoma of the urinary bladder2016
Author(s)
Kawasaki T, Suzuki M, Sato A, Yashima-Abo A, Satoh T, Kato R, Kato Y, Obara W, Shimoyama T, Ishida Y, Sugai T
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Journal Title
J Clin Pathol
Volume: 69
Issue: 1
Pages: 89-92
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Non-Islet Cell Tumor Hypoglycemia Is Caused by Big IGF-II in a Patient with a Carcinosarcoma of the Uterus2015
Author(s)
Honma H, Takahashi Y, Matsui M, Satoh T, Fukuda I, Takahashi K, Takebe N, Nagasawa K, Ono M, Sasai T, Kajiwara T, Sugai T, Satoh J, Ishigaki Y.
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Journal Title
Internal Medicine
Volume: 54
Issue: 24
Pages: 3165-3169
DOI
NAID
ISSN
0918-2918, 1349-7235
Related Report
Peer Reviewed / Open Access
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