Project/Area Number |
26670297
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Medical Physics and Radiological Technology
|
Research Institution | Yamagata University |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
MIYACHI Yoshiyuki 山形大学, 理学部, 准教授 (50334511)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | MRI / 動的核偏極 / ゼノン / 超偏極 / キセノン / スピン / 能動核偏極 |
Outline of Final Research Achievements |
In order to realize hyper polarization of 139 Xe nuclei within a scope of higher level MRI, we have tried to develop a new method of uniform diffusion of free radical molecules, which are necessary for dynamic nuclear polarization,using a ball mill. Using SF6 which is less expensive than Xe, we made its solidification at low temperature, milling and mixing with a free radical (TEMPOL) and ESR measurement. Modifying a ball mill which is available in market, we made a system in which one can perform ball milling for 1 hour at a temperature of 150K. And we succeeded to make its ESR measurement in the temperature range from 100K to room temperature. Looking at the ESR spectrum, we tried to understand degree of uniformity of the free radical. However, it turned out it is difficult because we have no reference signal when the uniform distribution is realized. We found that there is additional problem to be solved in future.
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