Research for optimization of bolus shape for carbon-ion therapy

Research Project

Project/Area Number	26670298
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Multi-year Fund
Research Field	Medical Physics and Radiological Technology
Research Institution	University of Tsukuba
Principal Investigator	Takada Yoshihisa 筑波大学, 数理物質系, 教授 (00134205)
Project Period (FY)	2014-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000) Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	bolusの自動最適化設計 / single-material bolus / bi-material bolus / 炭素イオン線治療 / bolusの自動最適化 / 炭素イオン線
Outline of Final Research Achievements	A range-compensating bolus is a key device to conform the irradiation field to the target boundary in carbon-ion therapy. We have developed a novel automated design method of the bolus by putting subscription doses in and around the target and OARs(Organs At Risk) and obtaining a bolus shape giving the optimum dose distribution by use of the least-square method.　We have improved dose distribution in and around the target and OARs using the method. We have shown that dose in the OAR can be decreased significantly while keeping the dose uniformity in the target by using the bolus designed by the method.

Report

(3 results)