| Project/Area Number |
26670304
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical Physics and Radiological Technology
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
Fukuchi Tomonori 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, 研究員 (40376546)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 核医学イメージング / 陽電子放射断層撮影 / PET / 陽電子 / 陽電子寿命 / 動物実験 / 核医学 / イメージング / 放射線 / 対消滅ガンマ線 / 脱励起ガンマ線 |
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| Outline of Final Research Achievements |
We developed a new positron emission tomography system, which can measure not only tracer distribution but also positron lifetime. Developed system provides information of positron lifetime as time difference between detection of de-excitation gamma-ray and annihilation gamma-ray, in addition to coincidence measurement of annihilation gamma-ray for the PET imaging. The positron lifetime changes depending on the oxygen concentration, molecular structure, temperature, electron density and so on. Therefore, in addition to information of the tracer distribution, positron lifetime in each organ or tissue provide various information of living organisms.
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