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Behavioral genetic study on human mate choice and reproductive behavior related to the genetic diversity

Research Project

Project/Area Number 26670328
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Research InstitutionNational Center for Global Health and Medicine (2016-2017)
The University of Tokyo (2014-2015)

Principal Investigator

Shimizu-Furusawa Hana  国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員 (80401032)

Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords配偶者選択 / 次世代 / 遺伝的多様性 / 異胞 / インドネシア / 繁殖 / 近親婚 / DNAメチル化 / 血縁淘汰 / 進化生物学
Outline of Final Research Achievements

The aim of this study was to reveal some biological aspects of social regulation on marriage system in relation to human mate choice. The study population was Sumbanese residents in East Nusa Tenggara Province, Indonesia, where the habitants prefer cross-cousin marriage ancestrally and traditionally. Their fertility as well as number of dead children under 15-years old in consanguineous marriage was higher than that of non-consanguineous marriage. It is suggested that offspring born to parents of consanguineous marriage might have more influence on genetic diversity within one’s lineage by their choice of their marital partners and that arranged marriage by parents might contribute more production of half-sibling with a biologically different father. Such a social regulation related to human reproductive behavior could possibly contribute to recruitment of heterozygous genotype and avoid loss of genetic diversity.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 2015 Other

All Int'l Joint Research (2 results) Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (2 results)

  • [Int'l Joint Research] Diponegoro University/Hasanuddin University(Indonesia)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Diponegoro University/Hasanuddin University(Indonesia)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Differences in the responses of three plasma selenium-containing proteins in relation to methylmercury-exposure through consumption of fish/whales.2017

    • Author(s)
      Ser, PH., Omi, S., Shimizu-Furusawa, H., Yasutake, A., Sakamoto, M., Hachiya, N., Konishi, S., Nakamura, M., and Watanabe, C.
    • Journal Title

      Toxicology Letters

      Volume: 267 Pages: 53-58

    • DOI

      10.1016/j.toxlet.2016.12.001

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association of cadmium and arsenic exposure with salivary telomere length in adolescents in Terai, Nepal.2016

    • Author(s)
      Fillman, T., Shimizu-Furusawa, H., Ng, C.F.S., Parajuli, R.P., and Watanabe, C.
    • Journal Title

      Environmental Research,

      Volume: 149 Pages: 8-14

    • DOI

      10.1016/j.envres.2016.04.037

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging2016

    • Author(s)
      Yoshida, M., Lee, JY., Shimizu-Furusawa, H., Satoh, M., and Watanabe, C.
    • Journal Title

      Fundamental Toxicological Sciences

      Volume: 3 Issue: 4 Pages: 185-193

    • DOI

      10.2131/fts.3.185

    • NAID

      130005158222

    • ISSN
      2189-115X
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Non-monotonic relationships between arsenic and selenium excretion and its implication on arsenic methylation pattern in a Bangladeshi population.2015

    • Author(s)
      Yoshida, N., Inaoka. T., Sultana, N, Ahmad, S.A., Mabuchi, A., Shimizu, H., Watanabe, C.
    • Journal Title

      Environmental Research

      Volume: 140 Pages: 300-307

    • DOI

      10.1016/j.envres.2015.03.019

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Delta-aminolevulinic acid dehydratase (ALAD) polymorphism in lead exposed Bangladeshi children and its effect on urinary aminolevulinic acid (ALA).2015

    • Author(s)
      Tasmin, S., Furusawa, H., Ahmad, SA., Faruquee, MH., Watanabe, C.
    • Journal Title

      Environmental Research

      Volume: 136 Pages: 318-323

    • DOI

      10.1016/j.envres.2014.08.045

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Arsenic exposure increases maternal but not cord serum immunoglobulin G level in Bangladesh2015

    • Author(s)
      Ser, PH., Bilkis, B., Fatema, J., Fatema, K., Nasrin, R., Rabeya, Y., Furusawa, H., Liaquat, A., Akhtar, A., Watanabe, C.
    • Journal Title

      Pediatrics International

      Volume: 57(1)(in press) Issue: 1 Pages: 119-125

    • DOI

      10.1111/ped.12396

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] チャオプラヤ川流域の大洪水が住民に与えたインパクトと被災世帯の水質変動.2015

    • Author(s)
      古澤華, モークノイ・デイジー, ジャイカンラヤ・チャート, タントゥラカルナパ・クライチャット, 渡辺知保.
    • Organizer
      第85回日本衛生学会総会
    • Place of Presentation
      和歌山
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] Effects of cadmium exposure on salivary telomere length in adolescents in Terai, Nepal.2015

    • Author(s)
      Fillman, T., Shimizu, H., Parajuli, R., and Watanabe, C.
    • Organizer
      The 54th Society of Toxigology Annual Meeting
    • Place of Presentation
      San Diego, California, USA
    • Year and Date
      2015-03-22 – 2015-03-26
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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