Behavioral genetic study on human mate choice and reproductive behavior related to the genetic diversity
Project/Area Number |
26670328
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Hygiene and public health
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Research Institution | National Center for Global Health and Medicine (2016-2017) The University of Tokyo (2014-2015) |
Principal Investigator |
Shimizu-Furusawa Hana 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員 (80401032)
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Project Period (FY) |
2014-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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Keywords | 配偶者選択 / 次世代 / 遺伝的多様性 / 異胞 / インドネシア / 繁殖 / 近親婚 / DNAメチル化 / 血縁淘汰 / 進化生物学 |
Outline of Final Research Achievements |
The aim of this study was to reveal some biological aspects of social regulation on marriage system in relation to human mate choice. The study population was Sumbanese residents in East Nusa Tenggara Province, Indonesia, where the habitants prefer cross-cousin marriage ancestrally and traditionally. Their fertility as well as number of dead children under 15-years old in consanguineous marriage was higher than that of non-consanguineous marriage. It is suggested that offspring born to parents of consanguineous marriage might have more influence on genetic diversity within one’s lineage by their choice of their marital partners and that arranged marriage by parents might contribute more production of half-sibling with a biologically different father. Such a social regulation related to human reproductive behavior could possibly contribute to recruitment of heterozygous genotype and avoid loss of genetic diversity.
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Report
(5 results)
Research Products
(10 results)
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[Journal Article] Differences in the responses of three plasma selenium-containing proteins in relation to methylmercury-exposure through consumption of fish/whales.2017
Author(s)
Ser, PH., Omi, S., Shimizu-Furusawa, H., Yasutake, A., Sakamoto, M., Hachiya, N., Konishi, S., Nakamura, M., and Watanabe, C.
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Journal Title
Toxicology Letters
Volume: 267
Pages: 53-58
DOI
Related Report
Peer Reviewed
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[Journal Article] Association of cadmium and arsenic exposure with salivary telomere length in adolescents in Terai, Nepal.2016
Author(s)
Fillman, T., Shimizu-Furusawa, H., Ng, C.F.S., Parajuli, R.P., and Watanabe, C.
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Journal Title
Environmental Research,
Volume: 149
Pages: 8-14
DOI
Related Report
Peer Reviewed
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[Journal Article] Non-monotonic relationships between arsenic and selenium excretion and its implication on arsenic methylation pattern in a Bangladeshi population.2015
Author(s)
Yoshida, N., Inaoka. T., Sultana, N, Ahmad, S.A., Mabuchi, A., Shimizu, H., Watanabe, C.
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Journal Title
Environmental Research
Volume: 140
Pages: 300-307
DOI
Related Report
Peer Reviewed
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[Journal Article] Arsenic exposure increases maternal but not cord serum immunoglobulin G level in Bangladesh2015
Author(s)
Ser, PH., Bilkis, B., Fatema, J., Fatema, K., Nasrin, R., Rabeya, Y., Furusawa, H., Liaquat, A., Akhtar, A., Watanabe, C.
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Journal Title
Pediatrics International
Volume: 57(1)(in press)
Issue: 1
Pages: 119-125
DOI
Related Report
Peer Reviewed
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[Presentation] Effects of cadmium exposure on salivary telomere length in adolescents in Terai, Nepal.2015
Author(s)
Fillman, T., Shimizu, H., Parajuli, R., and Watanabe, C.
Organizer
The 54th Society of Toxigology Annual Meeting
Place of Presentation
San Diego, California, USA
Year and Date
2015-03-22 – 2015-03-26
Related Report