Next-generation sequence of cancer-related genes in digestive organ cancers using clinical samples
| Project/Area Number |
26670380
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Gastroenterology
|
|---|
| Research Institution | University of Yamanashi |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 消化器癌 / 次世代シークエンス解析 / レーザーキャプチャーマイクロダイゼクション / 早期癌 / 次世代シークエンス / IPMN / 膵神経内分泌腫瘍 / 早期胃癌 / 早期食道癌 / 次世代シークエンサー / 膵管内乳頭粘液性腫瘍 / GNAS変異 / 分子標的薬 |
|---|
| Outline of Final Research Achievements |
Recent technical advancement of genetic analyses has enabled us to discover many cancer-related mutations in various cancers. We then have to clarify the clinical significance of these gene mutations. In this study, we conducted cancer-related gene analysis in cases with hepatocellular carcinoma, early esophageal carcinoma, early gastric carcinoma and intraductal papillary mucinous neoplasms that are known as precursor lesions of pancreatic cancer. We have found the relation between tumor mutations and several clinical characteristics.
|
Report
(3 results)
Research Products
(12 results)
-
[Journal Article] Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.2016
Author(s)
Kawai-Kitahata F, Asahina Y, Tanaka S, Kakinuma S, Murakawa M, Sayuri Nitta S, Watanabe T, Otani S, Taniguchi M, Goto F, Nagata H, Kaneko S, Tasaka-Fujita M, Nishimura-Sakurai Y, Azuma S, Itsui Y, Nakagawa M, Tanabe M, Takano S, Fukasawa M, Sakamoto M, Maekawa S, Enomoto N, Watanabe M.
-
Journal Title
Journal of Gastroenterology
Volume: 51
Issue: 5
Pages: 473-486
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
