| Project/Area Number |
26670456
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Endocrinology
|
|---|
| Research Institution | Yamagata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
Hotta Junichi 山形大学, 大学院理工学研究科, 准教授 (80301919)
Furusawa Hiroyuki 山形大学, 大学院理工学研究科, 准教授 (60345395)
Kutsuzawa Koichi 東京工業大学, 大学院生命理工学研究科, 研究員 (90572066)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 間葉系幹細胞 / バイオマテリアル / 再生医療 / Wntシグナル / 細胞増殖 / 骨分化 / 脂肪分化 / 組換えタンパク質 / 培養基板 |
|---|
| Outline of Final Research Achievements |
The proteins inducible of osteogenesis and adipogenesis are tried to immobilized to the substrate for the regulation of mesenchymal stem cell differentiation. Here, Wnt protein was successfully immobilized to the substrates to regulate cell growth and intracellular signaling.
|
