| Project/Area Number |
26670459
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Kobe University |
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Principal Investigator |
Takahashi Yutaka 神戸大学, 医学(系)研究科(研究院), 准教授 (70301281)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUOKA Hidenori 神戸大学, 医学部附属病院, 助教 (80622068)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 下垂体 / 腫瘍 / 原因 / 疾患特異的iPS細胞 / 下垂体疾患 / 先天性下垂体低形成 / 下垂体腫瘍 / iPS細胞 |
|---|
| Outline of Final Research Achievements |
To clarify the pathogenesis and medical treatment of functional pituitary adenoma, we have performed a comprehensive genetic analysis of the GH-producing pituitary adenoma. Regarding Cushing’s disease, we performed a microarray analysis and screened molecular targeted therapy using primary culture tumor cells. We have further established a protocol for the differentiation from human iPS cells into pituitary in vitro. We have published 15 English papers and 13 Japanese papers.
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