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Development of novel therapies for childhood cancers and congenital anomaly syndromes using integrated genetic scanning

Research Project

Project/Area Number 26670493
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Pediatrics
Research InstitutionThe University of Tokyo

Principal Investigator

Takita Junko  東京大学, 医学部附属病院, 准教授 (00359621)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords広汎性発達障害 / 精神運動発達遅滞 / 自閉症 / 神経芽腫 / 横紋筋肉腫 / Ewing肉腫 / 発達障害 / 次世代シークエンサー / エクソーム解析
Outline of Final Research Achievements

We performed exome sequencing of 3 mental retardation cases with solid tumors. Case 1 was a 4 year-old boy who developed neuroblastoma and suffered from intellectual disorder. Case 2 was 7 year-old boy with rhabdomyosarcoma and developmental disorder with minor anomalies. Case 3 was 24 year-old man with autism and Ewing sarcoma. ALK mutation was shared in primary and relapsed tumor samples of Case 1, whereas no shared mutation was detected in Case 2. A novel germline mutations of CSMD2, which is one of target genes of familial myoclonus was detected in Case 1. In addition, a novel gernline mutation of CNTN6 was found in Case 2, which is thought to be involved in the neural development and tumorigenesis of ovarian cancer. Furthermore, APC and PTEN have been identified as germline mutations of Case 3. Our results suggests that CSMD2, CNTN6, APC and PTEN are involved in the common pathways of development delay and tumorigenesis

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (122 results)

All 2016 2015 2014

All Journal Article (35 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 35 results,  Open Access: 35 results,  Acknowledgement Compliant: 3 results) Presentation (87 results) (of which Int'l Joint Research: 8 results,  Invited: 3 results)

  • [Journal Article] Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults2016

    • Author(s)
      Takahiko Yasuda, Shinobu Tsuzuki, Masahito Kawazu, Fumihiko Hayakawa, Shinya Kojima, Toshihide Ueno, Naoto Imoto, Shinji Kohsaka, Akiko Kunita, Koichiro Doi, Toru Sakura, Toshiaki Yujiri, Eisei Kondo, Katsumichi Fujimaki, Yasunori Ueda, Yasutaka Aoyama, Shigeki Ohtake, Junko Takita, Eirin Sai, Masafumi Taniwaki, et al.
    • Journal Title

      Nature genetics

      Volume: in press Issue: 5 Pages: 409-417

    • DOI

      10.1038/ng.3535

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A case of SLE presenting with mixed type fulminant autoimmune hemolytic anemia.2016

    • Author(s)
      Hirano Y, Itonaga T, Yasudo H, Isojima T, Miura K, Harita Y, Sekiguchi M, Kato M, Takita J, Oka A.
    • Journal Title

      Pediatr Int.

      Volume: - Issue: 6 Pages: 527-530

    • DOI

      10.1111/ped.12849

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adults with germline CBL mutation complicated with juvenile myelomonocytic leukemia at infancy.2016

    • Author(s)
      Muraoka M, Okuma, C, Kanamitsu K, Ishida H, Kanazawa Y, Washino K, Seki M, Kato M, Takita J, Sato Y, Ogawa S, Tsukahara H, and Oda M.
    • Journal Title

      J Hum Genet

      Volume: - Issue: 6 Pages: 523-526

    • DOI

      10.1038/jhg.2016.8

    • NAID

      40020857008

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ALKR1275Q perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.2016

    • Author(s)
      Ueda T, Nakata Y, Yamasaki N, Oda H, Sentani K, Kanai A, Onishi N, Ikeda K, Sera Y, Honda ZI, Tanaka K, Sata M, Ogawa S, Yasui W, Saya H, Takita J, Honda H.
    • Journal Title

      Oncogene.

      Volume: 無 Issue: 34 Pages: 4447-4458

    • DOI

      10.1038/onc.2015.519

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Molecular genetic and cytogenetic analysis of a primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma.2016

    • Author(s)
      Kato K, Oh Y, Takita J, Gunji Y, Kobayashi C, Yoshimi A, Nakao T, Noma M, Koike K, Morimoto A, Iijima S, Hojo H, Tsuchida M.
    • Journal Title

      Int J Hematol.

      Volume: 103 Issue: 2 Pages: 196-201

    • DOI

      10.1007/s12185-015-1895-9

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genomic analysis of clonal origin of Langerhans cell histiocytosis following acute lymphoblastic leukemia2015

    • Author(s)
      2.Kato M, Seki M, Yoshida K, Sato Y, Oyama R, Arakawa Y, Kishimoto H, Taki T, Akiyama M, Shiraishi Y, Chiba K, Tanaka H, Mitsuiki N, Kajiwara M, Mizutani S, Sanada M, Miyano S, Ogawa S, Koh K, Takita J.
    • Journal Title

      British Journal of Haematology

      Volume: Nov 5 Issue: 1 Pages: 169-172

    • DOI

      10.1111/bjh.13841

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Somatic mosaic mutations of IDH1 and NPM1 associated with cup-like acute myeloid leukemia in a patient with Maffucci syndrome2015

    • Author(s)
      Akiyama M, Yamaoka M, Mikami-Terao Y, Ohyama W, Yokoi K, Arakawa Y, Takita J, Suzuki H, Yamada H
    • Journal Title

      International Journal of Hematology

      Volume: 102 Issue: 6 Pages: 723-8

    • DOI

      10.1007/s12185-015-1892-z

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Support for school reentry and relationships between children with cancer, peers, and teachers2015

    • Author(s)
      Soejima T, Sato I, Takita J, Koh K, Maeda M, Ida K, Kamibeppu K.
    • Journal Title

      Pediatr Int.

      Volume: 57 Issue: 6 Pages: 1101

    • DOI

      10.1111/ped.12730

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma.2015

    • Author(s)
      Seki M, Nishimura R, Yoshida K, Shimamura T, Shiraishi Y, Sato Y, Kato M, Chiba K, Tanaka H, Hoshino N, Nagae G, Shiozawa Y, Okuno Y, Hosoi H, Tanaka Y, Okita H, Miyachi M, Souzaki R, Taguchi T, Koh K, Hanada R, Kato K, Nomura Y, Akiyama M, Oka A, Igarashi T, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J.
    • Journal Title

      Nat Commun.

      Volume: 6 Issue: 1 Pages: 7557-7557

    • DOI

      10.1038/ncomms8557

    • NAID

      120005623266

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A case of atypical dyskeratosis congenita presenting as myelodysplastic syndrome and genetically diagnosed using whole-exome sequencing.2015

    • Author(s)
      Monoi A, Sugawa M, Kato M, Seki M, Watanabe K, Yoshida K, Sakaguchi H, Hama A, Ogawa S, Oka A, Takita J.
    • Journal Title

      Oncology Lett.

      Volume: -

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma2015

    • Author(s)
      Kawasaki Y, Makimoto M, Nomura K, Hoshino A, Hamashima T, Hiwatari M, Nakazawa A, Takita J, Yoshida T, Kanegane H.
    • Journal Title

      Clin Case Rep.

      Volume: 3 Issue: 3 Pages: 145

    • DOI

      10.1002/ccr3.183

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma: implications for targeted treatment.2015

    • Author(s)
      Lambertz I, Kumps C, Claeys S, Lindner S, Beckers A, Janssens E, Carter DR, Cazes A, Cheung BB, De Mariano M, De Bondt A, De Brouwer S, Delattre O, Gibbons J, Janoueix-Lerosey I, Laureys G, Liang C, Marshall GM, Porcu M, Takita J et all.
    • Journal Title

      Clin Cancer Res.

      Volume: 21 Issue: 14 Pages: 3327-39

    • DOI

      10.1158/1078-0432.ccr-14-2024

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Aggressive transformation of anaplastic large cell lymphoma with increased number of ALK-translocated chromosomes2015

    • Author(s)
      Hoshino A, Nomura K, Hamashima T, Isobe T, Seki M, Hiwatari M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Takita J, Kanegane H.
    • Journal Title

      Int J Hematol.

      Volume: 101 Issue: 2 Pages: 198

    • DOI

      10.1007/s12185-014-1701-0

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Allogeneic haematopoietic stem cell transplantation for infant acute lymphoblastic leukaemia with KMT2A (MLL) rearrangements: a retrospective study from the paediatric acute lymphoblastic leukaemia working group of the Japan Society for Haematopoietic Cell Transplantation.2015

    • Author(s)
      Kato M, Hasegawa D, Koh K, Kato K, Takita J, Inagaki J, Yabe H, Goto H, Adachi S, Hayakawa A, Takeshita Y, Sawada A, Atsuta Y, Kato K.
    • Journal Title

      Br J Haematol.

      Volume: 168 Issue: 4 Pages: 564-70

    • DOI

      10.1111/bjh.13174

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia.2015

    • Author(s)
      Koh K, Tomizawa D, Moriya Saito A, Watanabe T, Miyamura T, Hirayama M, Takahashi Y, Ogawa A, Kato K, Sugita K, Sato T, Deguchi T, Hayashi Y, Takita J, Takeshita Y, Tsurusawa M, Horibe K, Mizutani S, Ishii E.
    • Journal Title

      Leukemia

      Volume: 29(2) Issue: 2 Pages: 290-6

    • DOI

      10.1038/leu.2014.172

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient.2015

    • Author(s)
      Kawashima-Goto S, Imamura T, Seki M, Kato M, Yoshida K, Sugimoto A, Kaneda D, Fujiki A, Miyachi M, Nakatani T, Osone S, Ishida H, Taki T, Takita J, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Hosoi H.
    • Journal Title

      Int J Hematol.

      Volume: 101 Issue: 4 Pages: 411-6

    • DOI

      10.1007/s12185-014-1711-y

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma: implications for targeted treatment.2015

    • Author(s)
      Lambertz I, Kumps C, Claeys S, Lindner S, Beckers A, Janssens E, Carter DR, Cazes A, Cheung BB, De Mariano M, De Bondt A, De Brouwer S, Delattre O, Gibbons J, Janoueix-Lerosey I, Laureys G, Liang C, Marshall GM, Porcu M, Takita J et al.
    • Journal Title

      Clin Cancer Res.

      Volume: e pub ahead of print

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 小児の臨床検査 小児の遺伝子・染色体検査(解説)2015

    • Author(s)
      滝田 順子
    • Journal Title

      検査と技術

      Volume: 43 Pages: 58-62

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cyclic fluctuation of blood pressure in neonatal neuroblastoma.2014

    • Author(s)
      Fujishiro J, Sugiyama M, Ishimaru T, Uotani C, Tsuchida S, Takahashi N, Shiozawa R, Takita J, Iwanaka T.
    • Journal Title

      Pediatr Int.

      Volume: 56 Pages: 934-7

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Systemic lupus erythematosus complicated with liver cirrhosis in a patient with Papillon-Lefevre syndrome2014

    • Author(s)
      Yasudo, H., Ando, T., Takeuchi, M., Nakano, H., Itonaga, T., Takehara, H., Isojima, T., Miura, K., Harita, Y., Takita, J., and Oka, A.
    • Journal Title

      Lupus

      Volume: 23 Issue: 14 Pages: 1523-1527

    • DOI

      10.1177/0961203314547794

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic significance of leukopenia in childhood acute lymphoblastic leukemia.2014

    • Author(s)
      Shiozawa Y, Takita J, Kato M, Sotomatsu M, Koh K, Ida K, Hayashi Y.
    • Journal Title

      Oncol Lett.

      Volume: 7 Pages: 1169-74

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Relapsed Acute Lymphoblastic Leukemia with Unusual Multiple Bone Invasions: A case report.2014

    • Author(s)
      Hangai M, Watanabe K, Shiozawa R, Hiwatari M, Ida K, Takita J.
    • Journal Title

      Oncol Lett.

      Volume: 7 Pages: 991-3

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association.2014

    • Author(s)
      Tomiyama A, Uekita T, Kamata R, Sasaki K, Takita J, Ohira M, Nakagawara A, Kitanaka C, Mori K, Yamaguchi H, Sakai R.
    • Journal Title

      Cancer Res.

      Volume: 74(14) Issue: 14 Pages: 3790-3801

    • DOI

      10.1158/0008-5472.can-14-0241

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma2014

    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Shimamura T, Sato Y, Nishimura R, Okuno Y, Chiba K, Tanaka H, Kato K, Kato M, Hanada R, Nomura Y, Park MJ, Ishida T, Oka A, Igarashi T, Miyano S, Hayashi Y, Ogawa S, Takita J
    • Journal Title

      Cancer Res

      Volume: 74 Issue: 10 Pages: 2742-9

    • DOI

      10.1158/0008-5472.can-13-2470

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays2014

    • Author(s)
      Takita J, Chen Y, Kato M, Ohki K, Sato Y, Ohta S, Sugita K, Nishimura R, Hoshino N, Seki M, Sanada M, Oka A, Hayashi Y, Ogawa S
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 3 Pages: 258-64

    • DOI

      10.1111/cas.12352

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Japanese Dent disease has a wider clinical spectrum than Dent disease in Europe/USA : genetic and clinical studies of 86 unrelated patients with low-molecular-weight proteinuria2014

    • Author(s)
      Sekine T, Komoda F, Miura K, Takita J, Shimadzu M, et al
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Issue: 2 Pages: 376-84

    • DOI

      10.1093/ndt/gft394

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of the order of total body irradiation and chemotherapy on graft-versus-host disease2014

    • Author(s)
      Kato M, Shiozawa R, Koh K, Nagatoshi Y, Takita J, Ida K, Kikuchi A, Hanada R
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 36 Issue: 1 Pages: e9-e12

    • DOI

      10.1097/mph.0b013e318279e81c

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ectopic Neuroblastoma in Monozygotic Twins With Different Ages of Onset : Possible Twin-to-Twin Metastasis In Utero With Distinct Genetic Alterations After Birth2014

    • Author(s)
      Taketani T, Takita J, Ueyama J, Kanai R, Kumori K, Maruyama R, Hayashi K, Ogawa S, Fukuda S, Yamaguchi S
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 36 Issue: 2 Pages: 166-168

    • DOI

      10.1097/mph.0b013e318290c686

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【ビジュアル小児外科疾患のフォローアップ・プログラム-手術直後から遠隔期の問題点まで】 神経芽腫(解説/特集).2014

    • Author(s)
      滝田 順子
    • Journal Title

      小児外科

      Volume: 46 Pages: 1159-63

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 高用量シクロフォスファミドによるHLA一致同胞間骨髄幹細胞移植後に致死的心毒性をきたした一例2014

    • Author(s)
      渡邉 健太郎, 加藤 元博, 田中 淳, 中井 まりえ, 関 正史, 林 泰佑, 塩澤 亮輔, 樋渡 光輝, 吉田 健一, 小川 誠司, 松坂 恵介, 深山 正久, 滝田 順子, 岡 明.
    • Journal Title

      日本造血細胞移植学会雑誌

      Volume: 3 Pages: 120-3

    • NAID

      130004699749

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 次世代シーケンサーによる小児血液、腫瘍疾患における研究の進展 小児固形腫瘍における治療標的の探索2014

    • Author(s)
      滝田 順子
    • Journal Title

      日本小児血液・がん学会雑誌

      Volume: 51 Pages: 278-84

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【小児の治療指針】 血液・腫瘍 悪性リンパ腫(解説/特集)2014

    • Author(s)
      滝田 順子
    • Journal Title

      小児科診療

      Volume: 77 Pages: 486-8

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【急性リンパ性白血病(ALL)】 小児ALLの予後因子と治療(解説/特集)2014

    • Author(s)
      滝田 順子
    • Journal Title

      血液内科

      Volume: 68 Pages: 203-9

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 急性リンパ性白血病に対するゲノム解析の成果.2014

    • Author(s)
      滝田 順子
    • Journal Title

      血液内科

      Volume: 69 Pages: 713-9

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 急性リンパ性白血病(ALL).2014

    • Author(s)
      滝田 順子
    • Journal Title

      血液フロンティア

      Volume: 24 Pages: 55-63

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] TAL1 and MYB Abnormalities in Childhood T-Cell Acute Lymphoblastic Leukemia.2015

    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Kato M, Kimura S, Hanada R, Koh K, Miyano S, Imamura T, Horibeb K, Kiyokawa N, Manabe A, Ohara A, Hayashi Y, Oka A, Ogawa S, Takita J
    • Organizer
      57th American Society of Hematology Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2015-12-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Integrated genetic/epigenetic analysis of rhabdomyosarcoma.2015

    • Author(s)
      滝田順子
    • Organizer
      日本肉腫学会記念シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2015-12-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] 神経芽腫における統合的ゲノム解析.2015

    • Author(s)
      滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Genetic characterization of ALK positive neuroblastoma using genome-wide analysis combined with immunohistochemistry.2015

    • Author(s)
      Uryu K, Nishimura R, Yoshida K, Seki M, Hoshino N, Kato M, Hiwatari M, Oka A, Hayashi Y, Nakazawa A, Tajiri T, Nakagawara A, Miyano S, Ogawa S, Takita J
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] A comparison of the genetic feature in Down syndrome-ALL and non-Down syndrome-ALL.2015

    • Author(s)
      Uryu K, Yoshida K, Sek M, Hoshino N, Kato M, Hiwatari M, Oka A, Ogawa S, Miyano S, Kikuchi A, Takita J
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 小児胚細胞腫瘍のゲノム網羅的解析.2015

    • Author(s)
      久保田泰央,関正史,樋渡光輝,加藤元博,吉田健一,佐藤悠佑,白石友一,千葉健一,田中洋子,宮野悟,康勝好,林泰秀,小川誠司,滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Identification of subgroup of pediatric ALL who can and cannot be cured by short maintenance therapy.2015

    • Author(s)
      Kato M,Manabe A, Ishimaru S, Seki M, Yoshida K, Sato Y, Tomizawa D, Hasegawa D, Inukai T, Arakawa Yi, Aoki T, Okuya M, Kaizu K, Kato K, Taneyama Y, Takita J, Ogawa Si, Koh K, Tsuchida M, Ohara A
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 膵芽腫におけるゲノム異常を特徴付ける11p15.5ヘテロ接合生喪失とCTNNB1体細胞変異.2015

    • Author(s)
      関正史, 磯部知哉, 吉田健一, 白石友一, 千葉健一, 田中洋子, 佐藤悠介, 加藤元博, 井口晶裕, 濱麻人, 宗崎良太, 田口智章, 田中祐吉, 秋山政晴, 藤村純也, 井上彰子, 伊藤剛, 出口隆生, 宮野悟, 小川誠司, 滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] MLL遺伝子を含んだ3方向転座を有した乳児白血病の1例.2015

    • Author(s)
      樋渡光輝, 関正史, 加藤元博, 吉田健一, 小川誠司, 滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 甲状腺濾胞癌の発生を契機に生殖細胞のDICER1遺伝子異常を同定した2症例.2015

    • Author(s)
      吉田美沙, 村岡枝里香, 関正史, 吉田健一, 浜之上聡, 武山絵里子, 田中水緒, 後藤裕明, 宮野悟, 小川誠司, 滝田順子, 田中祐吉
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 過去10年間に当院で治療した小児骨肉腫の検討.2015

    • Author(s)
      半谷まゆみ, 関口昌央, 久保田泰央, 関正史, 樋渡光輝, 岡明, 滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] ユーイング肉腫再発時に甲状腺がん微小肺転移が発見された一例.2015

    • Author(s)
      関口昌央, 関正史, 加藤元博, 渡邉健太郎, 樋渡光輝, 丹羽隆善, 河野博隆, 岡明, 滝田順子
    • Organizer
      第57回日本小児血液・がん学会学術集会
    • Place of Presentation
      山梨
    • Year and Date
      2015-11-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 「小児がんにおける治療分子標的の探索」2015

    • Author(s)
      滝田順子
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Whole exome and transcriptome analyses in pediatric T-cell acute lymp hoblastic leukemia2015

    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Kato M, Imamura T, Hanada R, Miyano S, Hayashi Y, Ogawa S, Takita J
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] 2015 JCA-Mauvernay Award受賞記念講演 小児がんにおける治療標的分子の探索.2015

    • Author(s)
      滝田順子
    • Organizer
      第74回日本癌学会学術総会.
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] シンポジウム Integrated genetic/epigenetic analysis of pediatric solid tumors.2015

    • Author(s)
      滝田順子
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] エクソーム解析を用いた膵芽腫における腫瘍内ヘテロ不均一性の解析.2015

    • Author(s)
      関正史、磯部知弥、吉田健一、白石友一、千葉健一、田中洋子、佐藤悠佑、加藤元博、井口晶裕、宮野悟、小川誠司、滝田順子
    • Organizer
      第74回日本癌学会学術総会.
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 小児胚細胞腫瘍のゲノム網羅的な変異・構造解析.2015

    • Author(s)
      久保田泰央、関正史、吉田健一、佐藤悠佑、白石友一、千葉健一、田中洋子、樋渡光輝、加藤元博、宮野悟、林泰秀、小川誠司、滝田順子
    • Organizer
      第74回日本癌学会学術総会.
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 「がんゲノミクスに立脚した難治性小児がんの克服」~ゲノム研究の先に目指すもの~2015

    • Author(s)
      滝田順子
    • Organizer
      第19回山梨血液研究会サマーセミナー
    • Place of Presentation
      山梨
    • Year and Date
      2015-07-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] 精神発達遅滞を合併した左肺動脈起始異常症の診断においてSNPアレイが有用であった一例.2015

    • Author(s)
      西川由衣, 平田陽一郎, 田中優, 進藤孝洋, 犬塚亮, 清水信隆, 関正史, 滝田順子, 岡 明
    • Organizer
      第51回日本小児循環器学会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化膿性リンパ節炎を契機に診断した小児甲状腺乳頭がんの1例.2015

    • Author(s)
      磯島豪, 日高もえ, 加藤元博, 三浦健一郎, 安戸裕貴, 張田豊, 関正史, 滝田順子, 北中幸子, 岡 明
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-04-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] 特別企画「小児がんの克服を目指してベンチからベッドサイドへ」2015

    • Author(s)
      滝田順子
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Integrated genetic and epigenetic analysis defines novel molecular clusters in rhabdomyosarcoma.2015

    • Author(s)
      Seki M, Nishimura R, Yoshida K, Shimamura T, Shiraishi Y, Sato Y, Kato M, Chiba K, Tanaka H, Nagae G, Okuno Y, Hoso H, Tanaka Y, Ohkita H, Miyashi M, Taguchi T, Koh K, Hanada R, Oka A, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J
    • Organizer
      American Association for Cancer Research 2015
    • Place of Presentation
      Pensylvania, U.S,A,
    • Year and Date
      2015-04-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Clonal evolution and integral analysis of hepatoblastoma.2015

    • Author(s)
      Hoshino N, Seki M, Kato M, Yoshida K, Sato Y, Nakazawa A, Miyano S, Oka A, Iwanaka T, Hayashi Y, Ogawa S, Takita J
    • Organizer
      American Association for Cancer Research 2015
    • Place of Presentation
      Pensylvania, U.S,A,
    • Year and Date
      2015-04-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] RNA シークエンスを用いた年長児の神経芽腫症例の解析.2015

    • Author(s)
      樋渡光輝,関正史, 加藤元博, 吉田健一, 小川誠司, 滝田順子
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 統合的ゲノム解析によるLCH 合併T‐ALL における分子病態の解明.2015

    • Author(s)
      関正史,大山亮,加藤元博,吉田健一,荒川ゆうき,岸本宏志,花田良二,滝田順子,康勝好,岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 肝芽腫におけるエクソーム,トランスクリプトーム,SNPアレイを用いた統合的解析.2015

    • Author(s)
      星野論子,関正史,加藤元博,吉田健一,宗崎良太,田口智章,林泰秀,岩中督,滝田順子,岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 先天性孤立性肺静脈狭窄症を合併したMowat-Wilson症候群の1例.2015

    • Author(s)
      進藤考洋, 古谷憲孝, 関正史, 犬塚亮, 林泰佑, 平田陽一郎, 清水信隆, 生井良幸, 滝田順子, 岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 化膿性リンパ節炎を契機に診断した小児甲状腺乳頭がんの1例.2015

    • Author(s)
      日高もえ, 磯島豪, 加藤元博, 三浦健一郎, 安戸裕貴, 張田豊, 関正史, 滝田順子, 北中幸子, 岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] The Genetic landscape of neuroblastoma.2015

    • Author(s)
      Uryu K, Nishimura R, Yoshida K, Seki M, Kato M, Oka A, Hayashi Y, Tajiri T, Nakagawara A, Ogawa S, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      Osaka
    • Year and Date
      2015-04-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Integrated genetic and epigenetic analysis in rhabdomyosarcoma.2015

    • Author(s)
      Seki M, Yoshida K, Hosoi H, Tanaka Y, Okita H, Hanada R, Igarashi T, Oka A, Hayahshi Y, Ogawa S, Takita J:
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      Osaka
    • Year and Date
      2015-04-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Genetic alterations in ATM pathway related genes in neuroblastoma.2015

    • Author(s)
      Yoshida M, Kato M, Uryu K, Hoshino N, Seki M, Hiwatari M, Yoshida K, Oka A, Ogawa S, Hayashi Y, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      Osaka
    • Year and Date
      2015-04-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Clonal evolution and pathology in hepatoblastoma with familial adenomatous polyposis.2015

    • Author(s)
      Hoshino N, Seki M, Yoshida K, Kato M, Sato Y, Nakagawa A, Miyano S, Iwanaka T, Oka A, Ogawa S, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      Osaka
    • Year and Date
      2015-04-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Transcriptome profiling of neuroblastoma in higher stages by RNA-Sequencing.2015

    • Author(s)
      Hiwatari M, Seki M, Kato M, Yoshida K, Ogawa S, Oka A, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      Osaka
    • Year and Date
      2015-04-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 統合的ゲノム解析による小児腫瘍の病態解明2014

    • Author(s)
      滝田順子
    • Organizer
      第5回信濃町小児がんクラスター症例検討会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-15
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Whole Exome and Transcriptome Analyses in Pediatric T-Cell Acute Lymphoblastic Leukemia.2014

    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Kato M, Hanada R, Miyano S, ide Hayashi Y, Ogawa S, Takita J
    • Organizer
      56th Annual Meeting of American Society of Hematology
    • Place of Presentation
      San Francisco, U.S.A.
    • Year and Date
      2014-12-06 – 2014-12-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Transcriptome profiling of neuroblastoma by RNA-Seq.2014

    • Author(s)
      Hiwatari M, Seki M, Shiozawa R, Kato M, Yoshida K, Ogawa S, Takita J
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Integrated analysis of clonal evolution in hepatoblastoma with familial adenomatous polyposis.2014

    • Author(s)
      Hoshino N, Seki M, Yoshida K, Kato M, Sato Y, Kasahara M, Nakazawa A, Miyano S, Hayashi Y, Oka A, Iwanaka T, Takita J
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Landscape of genomic alteration of pediatric germ cell tumors.2014

    • Author(s)
      Shiozawa R, Seki M, Hoshino N, Yoshida K, Yoshida M, Uryu K, Hiwatari M, Kato M, Ogawa S, Oka A, Takita J
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Integrated genetic and epigenetic analysis defines novel molecular clusters in rhabdomyosarcoma.2014

    • Author(s)
      Seki M, Nishimura R, Yoshida K, Shimamura T, Shiraishi Y, Sato Y, Hoshino N, Nagae G, Okuno Y, Hosoi H, Tanaka Y, Okita H, Taguchi T, Hanada R, Oka A, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] The role of epigenetic dysregulation in neuroblastoma.2014

    • Author(s)
      Hoshino N, Seki M, Yoshida K, Kato M, Nishimura R, Sato Y, Miyano S, Nagae G, Hayashi Y, Oka A, Aburatani H, Iwanaka T, Ogawa S, Takita J
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 中心静脈カテーテル関連血流感染 (CRBSI) の予防に対する試みとその効果.2014

    • Author(s)
      渡邉健太郎,加藤元博,張田豊,関口昌央,塩澤亮輔,樋渡光輝,滝田順子,岡明
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 再発膵芽腫のマルチサンプリングによる腫瘍内不圴一およびクローン進化の考察.2014

    • Author(s)
      磯部知弥,関正史,吉田健一,白石友一,千葉健一,田中洋子,佐藤悠佑,加藤元博,井口晶裕,濱麻人,田中祐吉,宮野悟,小川誠司,岡明,滝田順子
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 重篤な慢性心不全を合併した21トリソミー児のAMKLに対する緩和的化学療法.2014

    • Author(s)
      関口昌央,加藤元博,渡邉健太郎,塩澤亮輔,樋渡光輝,林泰佑,平田陽一郎,滝田順子,岡明
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫におけるターゲット遺伝子の深々度シークエンス.2014

    • Author(s)
      瓜生久美子,西村力,吉田健一,関正史,星野論子,吉田美沙,加藤元博,樋渡光輝,岡明,林泰秀,田尻達郎,中川原章,滝田順子
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫におけるATM pathway 関連遺伝子の異常.2014

    • Author(s)
      吉田美沙,関正史,加藤元博,瓜生久美子,星野論子,西村力,樋渡光輝,吉田健一,岡明,小川誠司,林泰秀,滝田順子
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫再発2例に対する網羅的ゲノム解析.2014

    • Author(s)
      物井綾香,関正史,吉田健一,佐藤悠佑,加藤元博,樋渡光輝,星野論子,竹谷健,白石友一,千葉健一,田中洋子,宮野悟,岡明,林泰秀,小川誠司,滝田順子
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 先天性高悪性脳腫瘍の1例.2014

    • Author(s)
      木本豪,加藤元博,関口昌央,渡邉健太郎,塩澤亮輔,樋渡光輝,阿部浩幸,田中麻理子,武笠晃丈,滝田順子,岡明
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 慢性活動性EBV感染症の1倍検例.2014

    • Author(s)
      塩澤亮輔,樋渡光輝,加藤元博,田中淳,滝田順子,岡明
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] ALK陽性思春期神経芽腫に対するクリゾチニブの治療経験.2014

    • Author(s)
      松野良介,大貫裕太,藤田祥央,花村麻衣子,塚田大樹,秋山康介,外山大輔,池田祐一,関正史,加藤元博,樋渡光輝,滝田順子,磯山恵一
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 未分化大細胞型リンパ腫におけるALK転座染色体の過剰を伴った急性転化.2014

    • Author(s)
      星野顕宏,野村恵子,関正史,樋渡光輝,吉田健一,小川誠司,滝田順子,金兼弘和
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 腎静脈浸潤を認めた先天性間葉芽腎腫の一例.2014

    • Author(s)
      藤代準,杉山正彦,新井真理,石丸哲也,吉田真理子,魚谷千都恵,宮川亨平,加藤元博,滝田順子,土田晋也,高橋尚人,岩中督
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] FGFR−1増幅を伴う治療抵抗性未分化肉腫の1例.2014

    • Author(s)
      杣津晋平,合井久美子,渡邊敦,犬飼岳史,蓮田憲夫,高野邦夫,近藤哲夫,中澤温子,宮地充,細井創,滝田順子,後藤裕明,杉田莞爾
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Congenital and childhood plexiform (multinodular) cellar schwannoma の1乳児例.2014

    • Author(s)
      宮川亨平,藤代準,高見尚平,加藤怜子,出家亨一,魚谷千都絵,吉田真理子,石丸哲也,新井真理,杉山正彦,岩中督,加藤元博,渡邉健太郎,滝田順子,柴原順二
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 小児造血細胞移植後フォローアップ外来の取り組みと課題.2014

    • Author(s)
      岩崎美和,割田陽子,滝田順子,加藤元博,樋渡光輝,大友英子,宮里由香里
    • Organizer
      第56回日本小児血液・がん学会学術集会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2014-11-28 – 2014-11-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Integrated genomic analysis of pediatric solid tumors2014

    • Author(s)
      滝田順子
    • Organizer
      第11回日独先端科学(JGFoS)シンポジウム
    • Place of Presentation
      ブレーメン,ドイツ
    • Year and Date
      2014-10-31 – 2014-11-02
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Integrative genome analysis of T cell acute lymphoblastic leukemia with subsequent development of Langerhans cell histocytosis.2014

    • Author(s)
      Seki M, Kat M, Ohyama R, Yoshida K, Sato Y, Shiraishi Y, Chiba K, Tanaka H, Arakawa Y, Kishimot H, Sanada M, Miyano S, Oka A, Hanada R, Ogawa S, Koh K, Takita J
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-10-31 – 2014-11-02
    • Related Report
      2014 Research-status Report
  • [Presentation] Genome-wide Epigenetic and copy number analyses in Rhabdomyosarcoma.2014

    • Author(s)
      Seki M, Shimamura T, Yoshida K, Sato Y, Nishimura R, Kato M, Nagae G, Oka A, Miyano S, Aburatani H, Hayashi Y, Ogawa S, Takita J
    • Organizer
      46th Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2014-10-22 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] Genome-wide approach to identify gene targets of pancreatoblastoma.2014

    • Author(s)
      Isobe T, Seki M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Sato Y, Kato M, Hama A, Tanaka Y, Miyano S, Hayashi Y, Ogawa S, Oka A, Takita J
    • Organizer
      46th Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2014-10-22 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] Allogeneic hematopoietic stem cell transplantation for infants with acute lymphoblastic leukemia: A retrospective study from the pediatric all working group of the JSHCT.2014

    • Author(s)
      Kato M, Hasegawa D, Koh K, Inagaki J, Kato K, Goto H, Takita J, Yabe H, Sawada A, Atsuta Y, Kato K
    • Organizer
      46th Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2014-10-22 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] The influences of school reentry support on relationships that adolescents with cancer share with peers and teachers.2014

    • Author(s)
      Soejima T, Sato I, Takita J, Koh K, Maeda M, Ida K, Kamibeppu K
    • Organizer
      46th Congress of the International Society of Paediatric Oncology
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2014-10-22 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 次世代シーケンサーによる小児胚細胞腫瘍の変異解析.2014

    • Author(s)
      塩澤亮輔,関正史,星野論子,吉田健一,吉田美沙,瓜生久美子,加藤元博,小川誠司,滝田順子,岡明
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫大規模検体におけるgenetic landscape と予後解析.2014

    • Author(s)
      瓜生久美子,西村力,吉田健一,関正史,星野論子,吉田美沙,加藤元博,樋渡光輝,林泰秀,田尻達郎,中川原章,小川誠司,滝田順子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫における11q領域に関連した責任遺伝子探索.2014

    • Author(s)
      吉田美沙,関正史,加藤元博,瓜生久美子,星野論子,西村力,樋渡光輝,吉田健一,岡明,小川誠司,林泰秀,滝田順子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] エクソーム解析とトランスクリプトーム解析を用いた肝芽腫における統合解析.2014

    • Author(s)
      星野論子,関正史,吉田健一,加藤元博,白石友一,佐藤悠佑,千葉健一,宮野悟,林泰秀,岩中督,岡明,小川誠司,滝田順子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 新規ALK結合蛋白質であるFlotillin-1は、ALKの細胞膜結合の調整節を介してALKシグナルを制御する.2014

    • Author(s)
      冨山新太,上北尚正,山口英樹,上野英明,滝田順子,佐々木一樹,中川原章,森健太郎,堺隆一
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 胸膜肺芽腫におけるDICER 1 RNase IIIB ドメイン変異のmiRNA産生への影響.2014

    • Author(s)
      関正史,吉田健一,白石友一,佐藤悠佑,島村徹平,千葉健一,田中洋子,花田良二,岡明,宮野悟,林泰秀,小川誠司,滝田順子
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 小児がんの病態解明と治療標的の探索~その征服を目指して~2014

    • Author(s)
      滝田順子
    • Organizer
      平成26年度TCCSG総会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-25
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Genome-Wide Methylation Analysis in Neuroblastoma.2014

    • Author(s)
      Seki M, Kato M, Ohyam R, Yoshida K, Sato Y, Shiraishi Y, Chiba K, Tanaka H, Arakaw Y, Kishimoto H, Sanada M, Miyano S, Oka A, Hanada R, Ogawa S, Koh K, Takit J
    • Organizer
      Advances in Neuroblastoma Research 2014
    • Place of Presentation
      Cologne, Germany
    • Year and Date
      2014-05-13 – 2014-05-16
    • Related Report
      2014 Research-status Report
  • [Presentation] Analysis for Neuroblastoma Tumors to Reveal Novel Target Using Next-Generation RNA Sequencing2014

    • Author(s)
      Hiwatari M, Seki M, Kato M, Yoshida K, Ogawa S, Takita J
    • Organizer
      Advances in Neuroblastoma Research 2014
    • Place of Presentation
      Cologne, Germany
    • Year and Date
      2014-05-13 – 2014-05-16
    • Related Report
      2014 Research-status Report
  • [Presentation] Genetic Landscapes of Childhood T-Cell Acute Lymphoblastic Leukemia.2014

    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Kato M, Hiwatari M, Sanada M, Hanada R, Miyano S, Oka A, Hayashi Y, Ogawa S, Takita J
    • Organizer
      Pediatric Academic Societies and Aisan Society for Pediatric Research 2014
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2014-05-03 – 2014-05-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Genome-wide analysis of T cell acute lymphoblastic leukemia with subsequent development of Langerhans cell histocytosis.2014

    • Author(s)
      Seki M, Kato M, Oyama R, Yoshida K, Sato Y, Shiraishi Y, Chiba K, Tanaka H, Arakawa Y, Kishimoto H, Miyano S, Oka A, Hanada R, Ogawa S, Koh K, Takita J
    • Organizer
      9th Biennial Childhood Leukemia Symposium
    • Place of Presentation
      Prague, Check Republic
    • Year and Date
      2014-04-28 – 2014-04-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 小児がんの克服を目指して”ベンチからベッドサイドへ”2014

    • Author(s)
      滝田順子
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-04-17 – 2014-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 統合的ゲノム解析によるLCH合併T−ALLにおける分子病態の解明.2014

    • Author(s)
      関正史,大山亮,加藤元博,吉田健一,荒川ゆうき,岸本宏志,花田良二,滝田順子,康勝好,岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-04-17 – 2014-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] RNA シークエンスを用いた年長児の神経芽腫症例の解析.2014

    • Author(s)
      樋渡光輝,関正史,加藤元博,吉田健一,小川誠司,滝田順子
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-04-17 – 2014-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 肝芽腫におけるエクソーム,トランスクリプトーム,SNPアレイを用いた統合的解析.2014

    • Author(s)
      星野論子,関正史,加藤元博,吉田健一,宗崎良太,田口智章,林泰秀,岩中督,滝田順子,岡明
    • Organizer
      第118回日本小児科学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-04-17 – 2014-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] The Genetic landscape of neuroblastoma.2014

    • Author(s)
      Uryu K, Nishimura R, Yoshida K, Seki M, Kato M, Oka A, Hayashi Y, Tajiri T, Nakagawara A, Ogawa S, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      グランキューブ大阪
    • Year and Date
      2014-04-15 – 2014-04-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Integrated genetic and epigenetic analysis in rhabdomyosarcoma.2014

    • Author(s)
      Seki M, Yoshida K, Hosoi H, Tanaka Y, Okita H, Hanada R, Igarashi T, Oka A, Hayahshi Y, Ogawa S, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      グランキューブ大阪
    • Year and Date
      2014-04-15 – 2014-04-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Genetic alterations in ATM pathway related genes in neuroblastoma.2014

    • Author(s)
      Yoshida M, Kato M, Uryu K, Hoshino N, Seki M, Hiwatari M, Yoshida K, Oka A, Ogawa S, Hayashi Y, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      グランキューブ大阪
    • Year and Date
      2014-04-15 – 2014-04-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Clonal evolution and pathology in hepatoblastoma with familial adenomatous polyposis.2014

    • Author(s)
      Hoshino N, Seki M, Yoshida K, Kato M, Sato Y, Nakagawa A, Miyano S, Iwanaka T, Oka A, Ogawa S, Takita J
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      グランキューブ大阪
    • Year and Date
      2014-04-15 – 2014-04-18
    • Related Report
      2014 Research-status Report
  • [Presentation] RNAシーケンス解析による横冠筋肉腫における新規転座の検索.2014

    • Author(s)
      関 正史, 西村 力, 吉田 健一, 加藤 元博, 樋渡 光輝, 宮野 悟, 林 泰秀, 小川 誠司, 滝田 順子, 岡 明
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 次世代シーケンサを用いた横紋筋肉腫の遺伝子変異全体図.2014

    • Author(s)
      西村 力, 吉田 健一, 白石 友一, 関 正史, 真田 昌, 岡 明, 林 泰秀, 宮野 悟, 小川 誠司, 滝田 順子
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 全エクソーム解析を用いた肝芽腫における網羅的ゲノム解析.2014

    • Author(s)
      星野 論子, 西村 力, 関 正史, 加藤 元博, 吉田 健一, 宮野 悟, 林 泰秀, 小川 誠司, 岡 明, 滝田 順子
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 次世代シークエンサーを用いた神経芽腫における11q領域の責任遺伝子探索.2014

    • Author(s)
      吉田 美沙, 関 正史, 星野 論子, 樋渡 光輝, 加藤 元博, 吉田 健一, 小川 誠司, 林 泰秀, 滝田 順子, 岡 明
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 神経芽腫120検体におけるゲノム異常と予後解析.2014

    • Author(s)
      瓜生 久美子, 関 正史, 加藤 元博, 星野 論子, 樋渡 光輝, 中川原 章, 林 泰秀, 小川 誠司, 滝田 順子, 岡 明
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 当院でのテイコプラニン標準投与における血中濃度解析.2014

    • Author(s)
      塩澤 亮輔, 渡邉 健太郎, 樋渡 光輝, 加藤 元博, 滝田 順子, 岡 明
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 再発を繰り返すランゲルハンス組織球症の1例.2014

    • Author(s)
      樋渡 光輝, 渡邉 健太郎, 塩澤 亮輔, 加藤 元博, 滝田 順子, 岡 明
    • Organizer
      第117回日本小児科学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2014-04-11 – 2014-04-13
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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