Generation of optical coherence tomography designed for the skin

• Project/Area Number: 26670530
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Dermatology
• Research Institution: Kyoto University
• Principal Investigator: KABASHIMA Kenji 京都大学, 医学(系)研究科(研究院), 准教授 (00362484)
• Project Period (FY): 2014-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: イメージング / 皮膚科学

Outline of Final Research Achievements

In dermatological field, the main procedures to evaluate the skin is only by looking and invasive skin biopsy. We sought to develop a new tool to visualize the skin non-invasively.
We have developed a new optical coherence tomography, especially designed for observing the human skin non-invasively.

Research Products

• [Journal Article] Intravital multiphoton imaging of cutaneous immune responses (2014)
  • Author(s): Kabashima K, Egawa G.
  • Journal Title: Journal of Investigative Dermatology Volume: 134 Issue: 11 Pages: 2680-4
  • DOI: 10.1038/jid.2014.225
  • Peer Reviewed
• [Journal Article] In vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines. (2014)
  • Author(s): Mizuno, R., Kamioka, Y., Kabashima, K., Imajo, M., Sumiyama, K., Nakasho, E., Ito, T., Hamazaki, Y., Okuchi, Y., Sakai, Y., Kiyokawa, E., and Matsuda, M.
  • Journal Title: J Exp Med Volume: 211 Issue: 6 Pages: 1123-36
  • DOI: 10.1084/jem.20132112
  • NAID: 120005439165
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Remarks] 京都大学皮膚科学教室
  • URL: http://www.kuhp.kyoto-u.ac.jp/~skin/index.html