| Project/Area Number |
26670535
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 社会行動 / 行動の定量評価 / 自閉スペクトラム症 / 表情解析 / 音声解析 / オキシトシン |
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| Outline of Final Research Achievements |
We quantitatively analyzed eye gaze, facial expression, and voice prosody during Autism Diagnostic Observation Schedule recorded in 54 videos. These videos were collected from our randomized, placebo-controlled, double blind and crossover within-subject-design clinical trial of six weeks continuous administration of intranasal oxytocin in 18 adult males with high-functioning autism spectrum disorders at baseline, after placebo treatment, and after oxytocin treatment. The results included a significant oxytocin-induced-decrease in ratio of neutral component of facial expression during real-life social interaction with others. The results are now under preparation for submission.
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