Development of haptic system and multi-modalityu integrated microscope
| Project/Area Number |
26670633
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
竹内 文也 旭川医科大学, 医学部, 准教授 (30281835)
大城 理 大阪大学, 基礎工学研究科, 教授 (90252832)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 蛍光信号 / 脳律動 / 脳血流解析 / 蛍光信号解析 / 顕微鏡 / カメラ / 定量化 / マルチバンド周波数 / 腫瘍蛍光 / Neuronavigation / Florescence / Sensory feedback / Virtual reality / 脳機能解析 / リアルタイム解析 / force feedback |
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| Outline of Final Research Achievements |
We developed a microscope, which equipped with a special system to analyze florescence signals intraoperatively and in real-time. Indocyanin green (ICG) is a wall-known drug, which had florescence signals of 800 nm in vascular structures. Our software automatically extracts ICG-siganls and analyze blood flow and speed in real-time and create reports. The evaluated blood flow was confirmed by mean-transit flow meter. 5-aminolevulinic acid is metabolized mainly in the malignant tissue and converted to Protoporphylin IX, which shows 630nm of florescence. The characteristic signals indicated malignant tissue, tumor margin and healthy tissue by spectral strength. The spectrometer is equipped on eye pieces on the microscope, which provide us real-time tissue characteristics. Above mentioned ideas are submitted to domestic and international patents. The first patent of ICG has been accepted in Japan.
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Report
(4 results)
Research Products
(113 results)
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[Journal Article] Risk factors for neurological worsening and symptomatic watershed infarction in internal carotid artery aneurysm treated by extracranial-intracranial bypass using radial artery graft2016
Author(s)
Matsukawa H, Tanikawa R, Kamiyama H, Tsuboi T, Noda K, Ota N, Miyata S, Oda J, Takeda R, Tokuda S, Kamada K
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Journal Title
J neurosurgery
Volume: 印刷中
Issue: 2
Pages: 239-246
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Long-term outcome and neuroradiologic changes after multiple hippocampal transection combined with multiple subpial transection or lesionectomy for temporal lobe epilepsy2016
Author(s)
Usami K, Kubota M, Kawai K, Kunii N, Matsuo T, Ibayashi K, Takahashi M, Kamada K, Momose T, Aoki S, Saito N
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Journal Title
Epilepsia
Volume: 57(6)
Issue: 6
Pages: 931-940
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Bypass Revascularization Applied to the Posterior Cerebral Artery2016
Author(s)
Ota N, Goehre F, Miyazaki T, Kinoshita Y, Matsukawa H, Yanagisawa T, Sakakibara F, Saito N, Miyata S, Noda K, Tsuboi T, Kamiyama H, Tokuda S, Kamada K, Tanikawa R
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Journal Title
World Neurosurgery
Volume: 96
Pages: 460-472
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Diffusion tensor tractography of normal facial and vestibulocochlear nerves.2015
Author(s)
Yoshino M, Kin T, Ito A, Saito T, Nakagawa D, Kamada K, Mori H, Kunimatsu A, Nakatomi H, Oyama H, Saito N
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Journal Title
Int J Comput Assist Radiol Surg
Volume: 10
Issue: 4
Pages: 383-392
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Feasibility of diffusion tensor tractography for preoperative prediction of the location of the facial and vestibulocochlear nerves in relation to vestibular schwannoma.2015
Author(s)
Yoshino M, Kin T, Ito A, Saito T, Nakagawa D, Ino K, Kamada K, Mori H, Kunimatsu A, Nakatomi H, Oyama H, Saito N.
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Journal Title
Acta Neurochir (Wien)
Volume: 157
Issue: 6
Pages: 939-946
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery2015
Author(s)
Korostenskaja M, Kamada K, Guger C, Salinas C M, Westerveld M, astillo E M, Salillas E, Chen Po-C, Harris E, Seddon I, Elsayed M, Kapeller C, Schaal A. Seo Joo-H, Baumgartner J, Lee Ki H.
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Journal Title
Journal of Pediatric Epilepsy
Volume: 4(4)
Issue: 04
Pages: 184-206
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Combined use of diffusion tensor tractography and multifused contrast-enhanced FIESTA for predicting facial and cochlear nerve positions in relation to vestibular schwannoma.2015
Author(s)
Yoshino M, Kin T, Ito A, Saito T, Nakagawa D, Ino K, Kamada K, Mori H, Kunimatsu A, Nakatomi H, Oyama H, Saito N.
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Journal Title
J Neurosurg.
Volume: 123
Issue: 6
Pages: 1480-88
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Proceedings of the Seventh International Workshop on Advances in Electrocorticography.2015
Author(s)
Ritaccio A, Matsumoto R, Morrell M, Kamada K, Koubeissi M, Poeppel D, Lachaux JP, Yanagisawa Y, Hirata M, Guger C, Schalk G
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Journal Title
Epilepsy Behav
Volume: 51
Pages: 312-320
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Book] Moter Imagery2015
Author(s)
Guger C, Kapeller C,Ortner R,Kamada K
Total Pages
92
Publisher
Nova Science Publishers,Inc.
Related Report
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