| Project/Area Number |
26670640
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Gifu University |
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Principal Investigator |
OHE Naoyuki 岐阜大学, 医学部附属病院, 准教授 (60362159)
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| Co-Investigator(Kenkyū-buntansha) |
矢野 大仁 岐阜大学, 大学院医学系研究科, 准教授 (00332685)
副田 明男 岐阜大学, 医学部附属病院, 助教 (20444276)
高木 俊範 岐阜大学, 医学部附属病院, 助教 (00452152)
澤田 重信 岐阜大学, 医学部附属病院, 医員 (40610415)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 脳腫瘍 / 脳腫瘍幹細胞 / CD133 / CD44 / CD15 / NCAM / CD56 / CXCR4 / 腫瘍マーカー |
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| Outline of Final Research Achievements |
Malignant brain tumors stem cells are the primary cause of tumor development, recurrence, and resistance to treatment. Cancer stem cells express stem cell-specific surface markers and can be isolated by using a cell analyzer. We analyzed about 20 kinds of surface markers such as CD133 and CD44 expressed in malignant brain tumor stem cells over a long period of time.
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