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In vitro bone generation trial using multi-walled carbon nanotube blocks

Research Project

Project/Area Number 26670658
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthopaedic surgery
Research InstitutionShinshu University

Principal Investigator

TANAKA Manabu  信州大学, 医学部附属病院, 医員 (30723069)

Co-Investigator(Kenkyū-buntansha) SATO Yoshinori  東北大学, 環境科学研究科, 准教授 (30374995)
HANIU Hisao  信州大学, 学術研究院医学系, 准教授 (30252050)
Co-Investigator(Renkei-kenkyūsha) SAITO Naoto  信州大学, 学術研究院保健学系, 教授 (80283258)
AOKI Kaoru  信州大学, 医学部, 准教授 (30467170)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsカーボンナノチューブ / 再生医療 / 整形外科
Outline of Final Research Achievements

Multi-walled carbon nanotubes were formed in a shape suitable for bone regeneration (CNTp), and evaluated the possibility of applications in bone regeneration medicine. We couldn't produce bones in vitro but CNTp showed good cell proliferation, bone conduction, and excellent capacity to hold and release of the drug sustainably. It was suggested that CNTp can be applied to regenerative medicine using tissue engineering not only as a filler of the bone defect, but also as a scaffold material transplanted by culturing cells and as a carrier for controlled release of drugs.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2016 2015 2014

All Presentation (5 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] 多孔質に成型した多層カーボンナノチューブブロック体の骨形成への影響2016

    • Author(s)
      田中学 齋藤直人 Mei Zhang 佐藤義倫 羽二生久夫 滝沢崇 野村博紀 小林伸輔  岡本正則 高梨誠司  青木薫  薄井雄企  加藤博之
    • Organizer
      第117回信州整形外科懇談会
    • Place of Presentation
      信州大学医学部
    • Year and Date
      2016-02-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] Porous Multi-Walled Carbon Nanotube block (p-MWCNT block) の骨形成への影響2015

    • Author(s)
      田中学 齋藤直人 Mei Zhang 佐藤義倫 羽二生久夫 滝沢崇 野村博紀 小林伸輔  岡本正則 高梨誠司  青木薫  薄井雄企  加藤博之
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] A capacity of porous multi-walled carbon nanotube blocks as scaffold of bone regeneration2015

    • Author(s)
      Tanaka M, Saito N, Zhang M, Sato Y, Haniu H, Takizawa T, Nomura H, Kobayashi S, Okamoto M, Takanashi S, Aoki K, Usui Y, Kato H.
    • Organizer
      12th Bone Biology Forum
    • Place of Presentation
      クロスウェーブ幕張
    • Year and Date
      2015-08-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of carbon nanotube blocks on bone regeneration2015

    • Author(s)
      Tanaka M, Saito N, Zhang M, Sato Y, Haniu H, Takizawa T, Nomura H, Kobayashi S, Okamoto M, Takanashi S, Aoki K, Usui Y, Kato H.
    • Organizer
      Sixth Symposium on Carbon Nanomaterials Biology, Medicine & Toxicology
    • Place of Presentation
      名古屋大学
    • Year and Date
      2015-06-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multi-Walled Carbon Nanotube (MWCNT) block の骨形成への影響2014

    • Author(s)
      田中学
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      城山観光ホテル(鹿児島)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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